Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Laser Ablation of Abnormal Neurological Tissue Using Robotic Neuroblate System (LAANTERN): Procedural Safety and Hospitalization

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Long-Term Effect of Decompressive Craniectomy on Intracranial Pressure and Possible Implications for Intracranial Fluid Movements

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Comparison of PED and FRED Flow Diverters for Internal Carotid Artery Aneurysms: A Propensity Score-Matched Cohort Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Clinical and histopathological predictors of outcome in malignant meningioma

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Adaptive hybrid surgery analysis (AHSA) for adjuvant gamma knife radiosurgery treatment of vestibular schwannoma residuals

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Response to: neurosurgical procedures performed during residency in Europe-preliminary numbers and time trends

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Surgical treatment for symptomatic ventriculus terminalis: case series and a literature review

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  • Robert C Rennert
  • Usman Khan
  • Jiri Bartek
  • Stephen B Tatter
  • Melvin Field
  • Brian Toyota
  • Peter E Fecci
  • Kevin Judy
  • Alireza M Mohammadi
  • Patrick Landazuri
  • Andrew E Sloan
  • Albert H Kim
  • Eric C Leuthardt
  • Clark C Chen
Vis graf over relationer

BACKGROUND: Stereotactic laser ablation (SLA) has demonstrated potential utility for a spectrum of difficult to treat neurosurgical pathologies in multiple small and/or retrospective single-institutional series. Here, we present the safety profile of SLA of intracranial lesions from the Laser Ablation of Abnormal Neurological Tissue using Robotic NeuroBlate System (LAANTERN; Monteris Medical) multi-institutional, international prospective observational registry.

OBJECTIVE: To determine the procedural safety of SLA for intracranial lesions.

METHODS: Prospective procedural safety and hospitalization data from the first 100 treated LAANTERN patients was collected and analyzed.

RESULTS: Mean age and baseline Karnofsky Performance Status (KPS) were 51(± 17) yr and 83(± 15), respectively. In total, 81.2% of patients had undergone prior surgical or radiation treatment. Most patients had a single lesion (79%) ablated through 1 burr hole (1.2 ± 0.7 per patient), immediately following a lesion biopsy. In total, >90% of the lesion was ablated in 72% of treated lesions. Average total procedural time was 188.2 ± 69.6 min, and average blood loss was 17.7 ± 55.6 ccs. The average length of intensive care unit (ICU) and hospital stays before discharge were 38.1 ± 62.7 h and 61.1 ± 87.2 h, respectively. There were 5 adverse events (AEs) attributable to SLA (5/100; 5%). After the procedure, 84.8% of patients were discharged home. There was 1 mortality within 30 d of the procedure (1/100; 1%), which was not attributable to SLA.

CONCLUSION: SLA is a safe, minimally invasive procedure with favorable postprocedural ICU and hospital utilization profiles.

OriginalsprogEngelsk
TidsskriftNeurosurgery
Vol/bind86
Udgave nummer4
Sider (fra-til)538-547
Antal sider10
ISSN0069-4827
DOI
StatusUdgivet - 1 apr. 2020

Bibliografisk note

© Congress of Neurological Surgeons 2019.

ID: 58984616