Large Porcine Model of Profound Acute Ischemic Cardiogenic Shock

Ole K Møller-Helgestad, Hanne B Ravn, Jacob E Møller

    15 Citationer (Scopus)

    Abstract

    Cardiogenic shock is one of the leading causes of death following acute myocardial infarction affecting 10% of patients with large myocardial infarcts with a subsequent mortality rate of 50%. Here we describe a large porcine model of acute ischemic cardiogenic shock. Acute left or right ventricular failure can be achieved with close to a 100% success rate by stepwise injection of microspheres into the left or right coronary artery, respectively, and the method allows for titration of heart failure to a prespecified level.

    OriginalsprogEngelsk
    TidsskriftMethods in molecular biology
    Vol/bind1816
    Sider (fra-til)343-352
    Antal sider10
    ISSN1064-3745
    DOI
    StatusUdgivet - 2018

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