Lacrimal gland lesions in Denmark between 1974 and 2007

Sara Linea Von Holstein, Marianne Hamilton Therkildsen, Jan Ulrik Prause, Göran Stenman, Volkert Dirk Siersma, Steffen Heegaard

59 Citationer (Scopus)

Abstrakt

Purpose:  To evaluate the incidence rate, distribution, patient characteristics and indications for surgical intervention of lacrimal gland lesions in Denmark between 1974 and 2007. Material and methods:  All biopsied/surgically removed lacrimal gland lesions in Denmark during the period 1974-2007 were identified by searching two population-based registries. Specimens were collected and re-evaluated. The following data were collected: age, gender, indications for surgical intervention and local recurrence. Results:  A total of 232 lesions from 210 patients with a histologically verified lesion of the lacrimal gland were included. The incidence rate of lacrimal gland lesions was 1.3/1 000 000/year. The overall annual age- and gender-adjusted incidence rate more than doubled during the study period, owing to an increase in non-malignant lesions. Approximately half of the lesions were neoplasms (119) and 55% (66) of these were malignant. Dacryops constituted 10% (24), inflammatory lesions 27% (62), normal tissue 12% (27), benign tumours 23% (53) and malignant tumours 29% (66). Patients with malignant neoplasms were significantly older than patients with benign neoplasms (63 versus 48 years, p 
OriginalsprogEngelsk
TidsskriftActa Ophthalmologica
Vol/bind91
Udgave nummer4
Sider (fra-til)349-354
Antal sider6
ISSN1755-375X
DOI
StatusUdgivet - jun. 2013

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