Lægemiddeldosering til overvægtige børn

Christina Gade; Hanne Rolighed Christensen; Helle Holst

Lægemiddeldosering til overvægtige børn

Christina Gade, Hanne Rolighed Christensen, Helle Holst

Abstract

The prevalence of obesity in children is increasing rapidly worldwide. Obese children have a higher use of medicinal products than their normal-weight peers. Several general physiological alterations associated with obesity have been described. However, the impact of these alterations on drug metabolism and its consequences for drug dosing in children remains largely unknown. Pharmacokinetic studies are of utmost importance in order to avoid undertreatment, adverse effects or even toxicity.

Bidragets oversatte titel	Drug dosage in obese children
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	177
Udgave nummer	44
Sider (fra-til)	V05150446
ISSN	0041-5782
Status	Udgivet - 26 okt. 2015

Emneord

Adult
Child
Dose-Response Relationship, Drug
Drug Dosage Calculations
Humans
Pediatric Obesity/metabolism
Pharmaceutical Preparations/administration & dosage
Pharmacokinetics

Citationsformater

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abstract = "The prevalence of obesity in children is increasing rapidly worldwide. Obese children have a higher use of medicinal products than their normal-weight peers. Several general physiological alterations associated with obesity have been described. However, the impact of these alterations on drug metabolism and its consequences for drug dosing in children remains largely unknown. Pharmacokinetic studies are of utmost importance in order to avoid undertreatment, adverse effects or even toxicity. ",

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TY - JOUR

T1 - Lægemiddeldosering til overvægtige børn

AU - Gade, Christina

AU - Christensen, Hanne Rolighed

AU - Holst, Helle

PY - 2015/10/26

Y1 - 2015/10/26

N2 - The prevalence of obesity in children is increasing rapidly worldwide. Obese children have a higher use of medicinal products than their normal-weight peers. Several general physiological alterations associated with obesity have been described. However, the impact of these alterations on drug metabolism and its consequences for drug dosing in children remains largely unknown. Pharmacokinetic studies are of utmost importance in order to avoid undertreatment, adverse effects or even toxicity.

AB - The prevalence of obesity in children is increasing rapidly worldwide. Obese children have a higher use of medicinal products than their normal-weight peers. Several general physiological alterations associated with obesity have been described. However, the impact of these alterations on drug metabolism and its consequences for drug dosing in children remains largely unknown. Pharmacokinetic studies are of utmost importance in order to avoid undertreatment, adverse effects or even toxicity.

KW - Adult

KW - Child

KW - Dose-Response Relationship, Drug

KW - Drug Dosage Calculations

KW - Humans

KW - Pediatric Obesity/metabolism

KW - Pharmaceutical Preparations/administration & dosage

KW - Pharmacokinetics

M3 - Review

C2 - 26509544

SN - 0041-5782

VL - 177

SP - V05150446

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 44

ER -

Lægemiddeldosering til overvægtige børn

Abstract

Emneord

Fingeraftryk

Citationsformater