Kræftdisponerende mutationer er hyppige hos børn og unge med kræft

Ulrik Kristoffer Stoltze; Anna Byrjalsen; Lisa Lyngsie Hjalgrim; Ayo Wahlberg; Ramneek Gupta; Anne-Marie Gerdes; Karin Wadt; Kjeld Schmiegelow

Kræftdisponerende mutationer er hyppige hos børn og unge med kræft

Ulrik Kristoffer Stoltze, Anna Byrjalsen, Lisa Lyngsie Hjalgrim, Ayo Wahlberg, Ramneek Gupta, Anne-Marie Gerdes, Karin Wadt, Kjeld Schmiegelow

1 Citationer (Scopus)

Abstract

Germ line mutations causing paediatric cancer predisposition syndromes (PCPSs) are more common than previously anticipated and are now recognised as a significant contributor to the incidence of childhood cancer. Advances in and increased clinical application of next-generation sequencing technologies have led to a rise in paediatric patients undergoing whole genome sequencing (WGS). This review focuses on the potential syndromes/diagnoses, which WGS may reveal in patients with childhood cancers, and highlights the clinical and psychosocial impact of PCPSs.

Bidragets oversatte titel	Germ line mutations causing paediatric cancer predisposition syndromes are common in children and adolescents with cancer
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	180
Udgave nummer	17
Sider (fra-til)	V07170566
ISSN	0041-5782
Status	Udgivet - 23 apr. 2018

Citationsformater

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abstract = "Germ line mutations causing paediatric cancer predisposition syndromes (PCPSs) are more common than previously anticipated and are now recognised as a significant contributor to the incidence of childhood cancer. Advances in and increased clinical application of next-generation sequencing technologies have led to a rise in paediatric patients undergoing whole genome sequencing (WGS). This review focuses on the potential syndromes/diagnoses, which WGS may reveal in patients with childhood cancers, and highlights the clinical and psychosocial impact of PCPSs.",

author = "Stoltze, {Ulrik Kristoffer} and Anna Byrjalsen and Hjalgrim, {Lisa Lyngsie} and Ayo Wahlberg and Ramneek Gupta and Anne-Marie Gerdes and Karin Wadt and Kjeld Schmiegelow",

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T1 - Kræftdisponerende mutationer er hyppige hos børn og unge med kræft

AU - Stoltze, Ulrik Kristoffer

AU - Byrjalsen, Anna

AU - Hjalgrim, Lisa Lyngsie

AU - Wahlberg, Ayo

AU - Gupta, Ramneek

AU - Gerdes, Anne-Marie

AU - Wadt, Karin

AU - Schmiegelow, Kjeld

PY - 2018/4/23

Y1 - 2018/4/23

N2 - Germ line mutations causing paediatric cancer predisposition syndromes (PCPSs) are more common than previously anticipated and are now recognised as a significant contributor to the incidence of childhood cancer. Advances in and increased clinical application of next-generation sequencing technologies have led to a rise in paediatric patients undergoing whole genome sequencing (WGS). This review focuses on the potential syndromes/diagnoses, which WGS may reveal in patients with childhood cancers, and highlights the clinical and psychosocial impact of PCPSs.

AB - Germ line mutations causing paediatric cancer predisposition syndromes (PCPSs) are more common than previously anticipated and are now recognised as a significant contributor to the incidence of childhood cancer. Advances in and increased clinical application of next-generation sequencing technologies have led to a rise in paediatric patients undergoing whole genome sequencing (WGS). This review focuses on the potential syndromes/diagnoses, which WGS may reveal in patients with childhood cancers, and highlights the clinical and psychosocial impact of PCPSs.

M3 - Tidsskriftartikel

C2 - 29717702

SN - 0041-5782

VL - 180

SP - V07170566

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

ER -

Kræftdisponerende mutationer er hyppige hos børn og unge med kræft

Abstract

Fingeraftryk

Citationsformater