Abstract
The ageing process is associated with somatic mutations in haematopoietic stem cells, which can lead to clonal haematopoiesis. Recently, clonal haematopoiesis has emerged as a risk factor for cardiovascular disease, and the underlying mechanisms likely involve heightened inflammatory responses in leukocytes derived from mutated clones.
Bidragets oversatte titel | Clonal haematopoiesis is possibly a risk factor for cardiovascular disease |
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Originalsprog | Dansk |
Artikelnummer | V04200299 |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 182 |
Udgave nummer | 4 |
ISSN | 0041-5782 |
Status | Udgivet - 2021 |
Emneord
- Cardiovascular Diseases/epidemiology
- Clonal Hematopoiesis
- Clone Cells
- Hematopoietic Stem Cells
- Humans
- Risk Factors