Kliniske implikationer af falsk forhøjet prostataspecifikt antigen

Josefine Freyberg, Hiba Iraqi, Thomas Helgstrand, Redas Trepiakas, Esther Agnete Jensen

Abstrakt

Heterophile antibodies can cause falsely elevated levels of prostate-specific antigen (PSA), which is illustrated in this case report with two patient cases. In the first case, the falsely elevated PSA resulted in thorough and unnecessary examinations with multiple transrectal biopsies causing psychological distress and a risk of infection. In the second case, a patient was diagnosed with prostate cancer, and falsely rising levels of PSA possibly resulted in prolonged treatment with medical castration. These cases underline the importance of suspecting interference, when clinical findings and PSA levels do not match.

Bidragets oversatte titelClinical implications of falsely elevated prostate-specific antigen
OriginalsprogDansk
ArtikelnummerV05220360
TidsskriftUgeskrift for Laeger
Vol/bind184
Udgave nummer38
ISSN0041-5782
StatusUdgivet - 19 sep. 2022

Emneord

  • Antibodies, Heterophile
  • Biopsy/methods
  • Humans
  • Male
  • Prostate
  • Prostate-Specific Antigen
  • Prostatic Neoplasms/therapy

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