Abstract
Many autoimmune diseases like rheumatoid arthritis (RA) show gender differences. RA is triggered by an interaction between genetic, hormonal, environmental and behavioural factors. 75% of cases are women under the age of 60; lover the age 60 the gender ratio is 1:1. Different genotypes predispose for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling.
| Bidragets oversatte titel | Gender differences in autoimmune diseases illustrated by rheumatoid arthritis |
|---|---|
| Originalsprog | Dansk |
| Tidsskrift | Ugeskrift for læger [online] |
| Vol/bind | 169 |
| Udgave nummer | 25 |
| Sider (fra-til) | 2440-2 |
| Antal sider | 3 |
| ISSN | 1603-6824 |
| Status | Udgivet - 18 jun. 2007 |
Emneord
- Arthritis, Rheumatoid
- Environmental Exposure
- Female
- Genetic Predisposition to Disease
- Humans
- Life Style
- Male
- Menopause
- Pregnancy
- Sex Characteristics
- Sex Factors
- Socioeconomic Factors