Kønsforskelle ved autoimmune sygdomme illustreret ved reumatoid artritis

2 Citationer (Scopus)

Abstrakt

Many autoimmune diseases like rheumatoid arthritis (RA) show gender differences. RA is triggered by an interaction between genetic, hormonal, environmental and behavioural factors. 75% of cases are women under the age of 60; lover the age 60 the gender ratio is 1:1. Different genotypes predispose for RA. Pregnancy often suppresses RA, as does oral contraception. Lactation, smoking (w), BMI > 30, heavy vibrations and certain dust particles (m) may trigger RA, while the effect of male hormones is uncertain. Future prevention should focus on environment, behavioural factors and genetic profiling.

Bidragets oversatte titelGender differences in autoimmune diseases illustrated by rheumatoid arthritis
OriginalsprogDansk
TidsskriftUgeskrift for læger [online]
Vol/bind169
Udgave nummer25
Sider (fra-til)2440-2
Antal sider3
ISSN1603-6824
StatusUdgivet - 18 jun. 2007

Emneord

  • Arthritis, Rheumatoid
  • Environmental Exposure
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Life Style
  • Male
  • Menopause
  • Pregnancy
  • Sex Characteristics
  • Sex Factors
  • Socioeconomic Factors

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