Is the treatment effect of IFN-beta restored after the disappearance of neutralizing antibodies?

P S Sorensen; Nils Koch-Henriksen; Esben Meulengracht Flachs; K Bendtzen

doi:10.1177/1352458508088942

Is the treatment effect of IFN-beta restored after the disappearance of neutralizing antibodies?

P S Sorensen, Nils Koch-Henriksen, Esben Meulengracht Flachs, K Bendtzen

25 Citationer (Scopus)

Abstract

To establish whether multiple sclerosis (MS) patients, who have lost the therapeutic effect of interferon-beta (IFN-beta) owing to neutralizing antibodies (NAbs) and subsequently revert from a NAb-positive to a NAb-negative state under continued IFN-beta-1b therapy, regain clinical effect after reversion.

Originalsprog	Engelsk
Tidsskrift	Multiple Sclerosis
Vol/bind	14
Udgave nummer	6
Sider (fra-til)	837-42
Antal sider	6
ISSN	1352-4585
DOI	https://doi.org/10.1177/1352458508088942
Status	Udgivet - 1 jul. 2008
Udgivet eksternt	Ja

Adgang til dokumentet

10.1177/1352458508088942

Citationsformater

@article{e55931f3085544aaa3b43088fe009364,

title = "Is the treatment effect of IFN-beta restored after the disappearance of neutralizing antibodies?",

abstract = "To establish whether multiple sclerosis (MS) patients, who have lost the therapeutic effect of interferon-beta (IFN-beta) owing to neutralizing antibodies (NAbs) and subsequently revert from a NAb-positive to a NAb-negative state under continued IFN-beta-1b therapy, regain clinical effect after reversion.",

author = "Sorensen, {P S} and Nils Koch-Henriksen and Flachs, {Esben Meulengracht} and K Bendtzen",

year = "2008",

month = jul,

day = "1",

doi = "10.1177/1352458508088942",

language = "English",

volume = "14",

pages = "837--42",

journal = "Multiple Sclerosis",

issn = "1352-4585",