Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Is the association between offspring intelligence and parents' educational attainment influenced by schizophrenia or mood disorder in parents?

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. The impact of schizophrenia and intelligence on the relationship between age and brain volume

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Social cognition in patients at ultra-high risk for psychosis: What is the relation to social skills and functioning?

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Polygenic Heterogeneity Across Obsessive-Compulsive Disorder Subgroups Defined by a Comorbid Diagnosis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. The Duffy-null genotype and risk of infection

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. A major role for common genetic variation in anxiety disorders

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Psychiatric comorbidity in individuals with bullous pemphigoid and all bullous disorders in the Danish national registers

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer
Results from twin, family, and adoption studies all suggest that general intelligence is highly heritable. Several studies have shown lower premorbid intelligence in individuals before the onset of both mood disorders and psychosis, as well as in children and adolescents at genetic high risk for developing schizophrenia. Based on these findings, we aim to investigate if the association between educational achievement in parents and intelligence in their offspring is influenced by schizophrenia or mood disorder in parents. In a large population-based sample of young adult male conscripts (n = 156,531) the presence of a mental disorder in the parents were associated with significantly lower offspring scores on a test of general intelligence, the Børge Priens Prøve (BPP), and higher educational attainment in parents was significantly associated with higher BPP test scores in offspring. A significant interaction suggested that the positive association between maternal education and offspring intelligence was stronger in offspring of mothers with schizophrenia compared to the control group (p = 0.03). The associations between parental education and offspring intelligence are also observed when restricting the sample to conscripts whose parents are diagnosed after 30 years of age. In conclusion, findings from this study show a more positive effect of education on offspring intelligence in mothers with schizophrenia compared to mothers from the control group. This effect could have both environmental and genetic explanations.
OriginalsprogEngelsk
TidsskriftSchizophrenia Research: Cognition
Vol/bind9
Sider (fra-til)18-22
Antal sider5
ISSN2215-0013
DOI
StatusUdgivet - sep. 2017

ID: 57356678