Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

Sophine B Krintel; Giuseppe Palermo; Julia S Johansen; Søren Germer; Laurent Essioux; Ryma Benayed; Laura Badi; Mikkel Østergaard; Merete L Hetland

doi:10.1097/FPC.0b013e3283544043

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

Sophine B Krintel, Giuseppe Palermo, Julia S Johansen, Søren Germer, Laurent Essioux, Ryma Benayed, Laura Badi, Mikkel Østergaard, Merete L Hetland

Kræftbehandling

61 Citationer (Scopus)

Abstrakt

Recently, two genome-wide association studies identified single nucleotide polymorphisms (SNPs) significantly associated with the treatment response to tumor necrosis factor α (TNFα) inhibitors in patients with rheumatoid arthritis (RA). We aimed to replicate these results and identify SNPs and the possible biological pathways associated with the treatment response to TNFα inhibitors.

Originalsprog	Engelsk
Tidsskrift	Pharmacogenetics and Genomics
Vol/bind	22
Udgave nummer	8
Sider (fra-til)	577-89
Antal sider	13
ISSN	1744-6872
DOI	https://doi.org/10.1097/FPC.0b013e3283544043
Status	Udgivet - 2012

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10.1097/FPC.0b013e3283544043

Citationsformater

Krintel, S. B., Palermo, G., Johansen, J. S., Germer, S., Essioux, L., Benayed, R., Badi, L., Østergaard, M., & Hetland, M. L. (2012). Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis. Pharmacogenetics and Genomics, 22(8), 577-89. https://doi.org/10.1097/FPC.0b013e3283544043

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis. / Krintel, Sophine B; Palermo, Giuseppe; Johansen, Julia S et al.

I: Pharmacogenetics and Genomics, Bind 22, Nr. 8, 2012, s. 577-89.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Krintel, SB, Palermo, G, Johansen, JS, Germer, S, Essioux, L, Benayed, R, Badi, L, Østergaard, M & Hetland, ML 2012, 'Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis', Pharmacogenetics and Genomics, bind 22, nr. 8, s. 577-89. https://doi.org/10.1097/FPC.0b013e3283544043

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abstract = "Recently, two genome-wide association studies identified single nucleotide polymorphisms (SNPs) significantly associated with the treatment response to tumor necrosis factor α (TNFα) inhibitors in patients with rheumatoid arthritis (RA). We aimed to replicate these results and identify SNPs and the possible biological pathways associated with the treatment response to TNFα inhibitors.",

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T1 - Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

AU - Krintel, Sophine B

AU - Palermo, Giuseppe

AU - Johansen, Julia S

AU - Germer, Søren

AU - Essioux, Laurent

AU - Benayed, Ryma

AU - Badi, Laura

AU - Østergaard, Mikkel

AU - Hetland, Merete L

PY - 2012

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AB - Recently, two genome-wide association studies identified single nucleotide polymorphisms (SNPs) significantly associated with the treatment response to tumor necrosis factor α (TNFα) inhibitors in patients with rheumatoid arthritis (RA). We aimed to replicate these results and identify SNPs and the possible biological pathways associated with the treatment response to TNFα inhibitors.

U2 - 10.1097/FPC.0b013e3283544043

DO - 10.1097/FPC.0b013e3283544043

M3 - Journal article

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EP - 589

JO - Pharmacogenetics and Genomics

JF - Pharmacogenetics and Genomics

SN - 1744-6872

IS - 8

ER -

Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis

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