Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers

Darren Plant, Edward Flynn, Hamdi Mbarek, Philippe Dieudé, François Cornelis, Lisbeth Arlestig, Solbritt Rantapää Dahlqvist, George Goulielmos, Dimitrios T Boumpas, Prodromos Sidiropoulos, Julia S Johansen, Lykke M Ørnbjerg, Merete Lund Hetland, Lars Klareskog, Andrew Filer, Christopher D Buckley, Karim Raza, Torsten Witte, Reinhold E Schmidt, Jane Worthington

    76 Citationer (Scopus)

    Abstract

    Genetic factors have a substantial role in determining development of rheumatoid arthritis (RA), and are likely to account for 50-60% of disease susceptibility. Genome-wide association studies have identified non-human leucocyte antigen RA susceptibility loci which associate with RA with low-to-moderate risk.
    OriginalsprogEngelsk
    TidsskriftAnnals of the Rheumatic Diseases
    Vol/bind69
    Udgave nummer8
    Sider (fra-til)1548-53
    Antal sider6
    ISSN0003-4967
    DOI
    StatusUdgivet - 1 aug. 2010

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