Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach

L L N Husemoen; T Skaaby; Torben Martinussen; T Jørgensen; B H Thuesen; C Kistorp; J Jeppesen; J P Thyssen; M Meldgaard; P B Szecsi; M Fenger; A Linneberg

doi:10.1038/ejcn.2013.233

Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach

L L N Husemoen, T Skaaby, Torben Martinussen, T Jørgensen, B H Thuesen, C Kistorp, J Jeppesen, J P Thyssen, M Meldgaard, P B Szecsi, M Fenger, A Linneberg

25 Citationer (Scopus)

Abstract

Background/Objectives:The aim was to examine the causal effect of vitamin D on serum adiponectin using a multiple instrument Mendelian randomization approach.Subjects/Methods:Serum 25-hydroxy vitamin D (25(OH)D) and serum total or high molecular weight (HMW) adiponectin were measured in two Danish population-based studies: the Inter99 study (6405 adults, 30-60 years) conducted in 1999-2001, and the MONICA10 study (2656 adults, 41-71 years) conducted in 1993-1994.Results:In the Inter99 study, serum 25(OH)D was positively associated with total adiponectin (the effect estimate in % per doubling of 25(OH)D was 4.78, 95% CI: 1.96, 7.68, P

Originalsprog	Engelsk
Tidsskrift	European Journal of Clinical Nutrition
Vol/bind	68
Sider (fra-til)	189-95
Antal sider	7
ISSN	0954-3007
DOI	https://doi.org/10.1038/ejcn.2013.233
Status	Udgivet - feb. 2014

Adgang til dokumentet

10.1038/ejcn.2013.233

Citationsformater

Husemoen, L. L. N., Skaaby, T., Martinussen, T., Jørgensen, T., Thuesen, B. H., Kistorp, C., Jeppesen, J., Thyssen, J. P., Meldgaard, M., Szecsi, P. B., Fenger, M., & Linneberg, A. (2014). Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach. European Journal of Clinical Nutrition, 68, 189-95. https://doi.org/10.1038/ejcn.2013.233

Husemoen, LLN, Skaaby, T, Martinussen, T, Jørgensen, T, Thuesen, BH, Kistorp, C, Jeppesen, J, Thyssen, JP, Meldgaard, M, Szecsi, PB, Fenger, M & Linneberg, A 2014, 'Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach', European Journal of Clinical Nutrition, bind 68, s. 189-95. https://doi.org/10.1038/ejcn.2013.233

@article{48e15f504b8442cc98cb6f4bb0a3dfae,

title = "Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach",

abstract = "Background/Objectives:The aim was to examine the causal effect of vitamin D on serum adiponectin using a multiple instrument Mendelian randomization approach.Subjects/Methods:Serum 25-hydroxy vitamin D (25(OH)D) and serum total or high molecular weight (HMW) adiponectin were measured in two Danish population-based studies: the Inter99 study (6405 adults, 30-60 years) conducted in 1999-2001, and the MONICA10 study (2656 adults, 41-71 years) conducted in 1993-1994.Results:In the Inter99 study, serum 25(OH)D was positively associated with total adiponectin (the effect estimate in % per doubling of 25(OH)D was 4.78, 95% CI: 1.96, 7.68, P",

author = "Husemoen, {L L N} and T Skaaby and Torben Martinussen and T J{\o}rgensen and Thuesen, {B H} and C Kistorp and J Jeppesen and Thyssen, {J P} and M Meldgaard and Szecsi, {P B} and M Fenger and A Linneberg",

year = "2014",

month = feb,

doi = "10.1038/ejcn.2013.233",

language = "English",

volume = "68",

pages = "189--95",

journal = "European Journal of Clinical Nutrition",

issn = "0954-3007",

publisher = "Springer Nature",

}

TY - JOUR

T1 - Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach

AU - Husemoen, L L N

AU - Skaaby, T

AU - Martinussen, Torben

AU - Jørgensen, T

AU - Thuesen, B H

AU - Kistorp, C

AU - Jeppesen, J

AU - Thyssen, J P

AU - Meldgaard, M

AU - Szecsi, P B

AU - Fenger, M

AU - Linneberg, A

PY - 2014/2

Y1 - 2014/2

N2 - Background/Objectives:The aim was to examine the causal effect of vitamin D on serum adiponectin using a multiple instrument Mendelian randomization approach.Subjects/Methods:Serum 25-hydroxy vitamin D (25(OH)D) and serum total or high molecular weight (HMW) adiponectin were measured in two Danish population-based studies: the Inter99 study (6405 adults, 30-60 years) conducted in 1999-2001, and the MONICA10 study (2656 adults, 41-71 years) conducted in 1993-1994.Results:In the Inter99 study, serum 25(OH)D was positively associated with total adiponectin (the effect estimate in % per doubling of 25(OH)D was 4.78, 95% CI: 1.96, 7.68, P

AB - Background/Objectives:The aim was to examine the causal effect of vitamin D on serum adiponectin using a multiple instrument Mendelian randomization approach.Subjects/Methods:Serum 25-hydroxy vitamin D (25(OH)D) and serum total or high molecular weight (HMW) adiponectin were measured in two Danish population-based studies: the Inter99 study (6405 adults, 30-60 years) conducted in 1999-2001, and the MONICA10 study (2656 adults, 41-71 years) conducted in 1993-1994.Results:In the Inter99 study, serum 25(OH)D was positively associated with total adiponectin (the effect estimate in % per doubling of 25(OH)D was 4.78, 95% CI: 1.96, 7.68, P

U2 - 10.1038/ejcn.2013.233

DO - 10.1038/ejcn.2013.233

M3 - Journal article

C2 - 24219894

SN - 0954-3007

VL - 68

SP - 189

EP - 195

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

ER -

Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater