Intravenøs administration af lipid ved forgiftning med lipofilt laegemiddel

Martin Skjønnemand, Jens Damgaard-Jensen, Bo Gottschau

Abstract

OBJECTIVE: To draw attention to the use of intravenous lipids in the treatment of cardiac arrests caused by overdosage of lipophilic drugs. Case reports and animal studies have shown beneficial use of lipids in severe intoxication. The literature is reviewed. CONCLUSION: Lipids have a place in the treatment of severe cardiac events caused by local analgesics for regional anaesthesia. Lipids should be readily available when regional anaesthesia is performed. National guidelines should be prepared. Lipids may also be an option in the treatment of intoxication with other lipophilic drugs.
Bidragets oversatte titelIntravenous administration of lipids in poisoning caused by local analgesics
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind173
Udgave nummer2
Sider (fra-til)120-3
Antal sider4
ISSN0041-5782
StatusUdgivet - 2011

Emneord

  • Anesthesia, Conduction
  • Animals
  • Arrhythmias, Cardiac
  • Emulsions
  • Fat Emulsions, Intravenous
  • Heart Arrest
  • Humans
  • Overdose
  • Phospholipids
  • Practice Guidelines as Topic
  • Resuscitation
  • Soybean Oil
  • Treatment Outcome

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