Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

Karoline Sidelmann Brinch, Paul M Tulkens, Francoise Van Bambeke, Niels Frimodt-Møller, Niels Høiby, Hans-Henrik Kristensen

37 Citationer (Scopus)

Abstract

Staphylococcus aureus survives inside eukaryotic cells. Our objective was to assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in comparison with established antistaphylococcal agents acting on the bacterial envelope with a distinct mechanism.
OriginalsprogEngelsk
TidsskriftJournal of Antimicrobial Chemotherapy
Vol/bind65
Udgave nummer8
Sider (fra-til)1720-4
Antal sider5
ISSN0305-7453
DOI
StatusUdgivet - 1 aug. 2010

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