Abstract
Antibiotics may reduce cardiovascular morbidity. We randomised 4372 patients with stable coronary heart disease in the CLARICOR trial to clarithromycin 500 mg (n = 2172) or placebo (n = 2200) daily for a fortnight. After 2.6 years we found significantly increased cardiovascular mortality among the clarithromycin patients. There is a need for studies to evaluate the safety of clarithromycin. There is presently no evidence to support the preventive effect of antibiotics on patients with coronary heart disease.
Bidragets oversatte titel | Intervention with clarithromycin in patients with stable coronary heart disease--the CLARICOR trial: secondary publication |
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Originalsprog | Dansk |
Tidsskrift | Ugeskrift for Laeger |
Vol/bind | 169 |
Udgave nummer | 6 |
Sider (fra-til) | 497-9 |
Antal sider | 3 |
ISSN | 0041-5782 |
Status | Udgivet - 5 feb. 2007 |