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Internodal function in normal and regenerated mammalian axons

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Following Wallerian degeneration, peripheral myelinated axons have the ability to regenerate and, given a proper pathway, establish functional connections with targets. In spite of this capacity, the clinical outcome of nerve regeneration remains unsatisfactory. Early studies have found that regenerated internodes remain persistently short though this abnormality did not seem to influence recovery in conduction. It remains unclear to which extent abnormalities in axonal function itself may contribute to the poor outcome of nerve regeneration.
OriginalsprogEngelsk
TidsskriftActa Physiologica
Vol/bind189
Udgave nummer2
Sider (fra-til)191-200
Antal sider10
ISSN1748-1708
DOI
StatusUdgivet - 2007

ID: 36747345