Interleukin-8 production from human somatotroph adenoma cells is stimulated by interleukin-1β and inhibited by growth hormone releasing hormone and somatostatin

Signe Diness Vindeløv, Marie-Louise Hartoft-Nielsen, Åse Krogh Rasmussen, Klaus Bendtzen, Michael Kosteljanetz, Anna-Maria Andersson, Ulla Feldt-Rasmussen

13 Citationer (Scopus)

Abstract

Pituitary adenomas cause morbidity and mortality due to their localization and influence on pituitary hormone secretion. Although the pathogenesis of pituitary adenomas is unclear, studies have indicated that cytokines are involved. We investigated the role of cytokines, in particular interleukin (IL)-8, in the pathogenesis of growth hormone (GH) producing tumours.
OriginalsprogEngelsk
TidsskriftGrowth Hormone & IGF Research
Vol/bind21
Udgave nummer3
Sider (fra-til)134-9
Antal sider6
ISSN1096-6374
DOI
StatusUdgivet - 2011

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