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Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Intelligence test scores before and after alcohol-related disorders - a longitudinal study of Danish male conscripts

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BACKGROUND: Existing studies on intellectual consequences of alcohol-related disorders are primarily cross-sectional and compare intelligence test scores of individuals with and without alcohol-related disorders; hence, mixing the influence of alcohol-related disorders and predisposing factors such as premorbid intelligence. In this large-scale study, the primary aim was to estimate associations of alcohol-related disorders with changes in intelligence test scores from early adulthood to late midlife.

METHODS: Data were drawn from a follow-up study on middle-aged men which included a re-examination of the same intelligence test as completed in young adulthood at military conscription (total analytic sample=2,499). Alcohol-related hospital diagnoses were obtained from national health registries, whereas treatment for alcohol problems was self-reported at follow-up. The analyses included adjustment for year of birth, retest interval, baseline IQ score, education, smoking, alcohol consumption, and comorbidity.

RESULTS: Individuals with alcohol-related hospital diagnoses (8%) had a significantly lower baseline IQ score (95.0 vs. 100.5, p<0.001) and a larger decline in IQ scores from baseline to follow-up (-8.5 vs. -4.8, p<0.001) than individuals without such diagnoses. The larger decline in IQ scores with alcohol-related hospital diagnoses remained statistically significant after adjustment for all the covariates. Similar results were revealed when IQ scores before and after self-reported treatment for alcohol problems (10%) were examined.

CONCLUSIONS: Individuals with alcohol-related disorders have a lower intelligence test score both in young adulthood and late midlife and these disorders, moreover, seem to be associated with more age-related decline in intelligence test scores. Thus, low mean intellectual ability observed in individuals with alcohol-related disorders is probably a result of both lower premorbid intelligence and more intellectual decline. This article is protected by copyright. All rights reserved.

OriginalsprogEngelsk
TidsskriftAlcoholism: Clinical and Experimental Research
ISSN0145-6008
DOI
StatusE-pub ahead of print - 6 aug. 2019

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This article is protected by copyright. All rights reserved.

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