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E-pub ahead of print

Injection of Steroid in Nasal Polyps: A Systematic Review

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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Vis graf over relationer

BACKGROUND: Chronic rhinosinusitis (CRS) is a common chronic condition classically divided into two phenotypes according to the presence or absence of nasal polyps. The effects of both medical and surgical treatment are often temporary, encouraging research into new treatment options.

METHODS: We performed a systematic review related to dosages, effects, side effects, and safety of intrapolyp steroid injection in patients with nasal polyps. We identified five studies with a total of 386 patients and 2490 intrapolyp steroid injections.

RESULTS: Treatment with intrapolyp steroid injection leads to a decrease in the Total Nasal Polyps Score (TNPS), Total Nasal Symptom Score (TNSS), and Lund-Mackay Score. The dosage regimens vary from 10 to 40 mg triamcinolone acetonide. Only two cases of temporary visual complications were reported.

CONCLUSION: This review found that intrapolyp steroid injection may be an effective and safe treatment for patients with nasal polyps. However, there exist no large, randomized, clinical trials. We found no association between dose and effect, or dose and the risk of visual complications.

OriginalsprogEngelsk
TidsskriftAmerican Journal of Rhinology & Allergy
Sider (fra-til)1945892420936198
ISSN1945-8924
DOI
StatusE-pub ahead of print - 24 jun. 2020

ID: 60287193