Initial experience with EUS-guided microbiopsy forceps in diagnosing pancreatic cystic lesions: A multicenter feasibility study (with video)

Bojan Kovacevic, John Gásdal Karstensen, Roald Flesland Havre, Khanh Do-Cong Pham, Marc Giovannini, Emanuele Dabizzi, Paolo Arcidiacono, Erwin Santo, Enrique Vazquez Sequeiros, Pia Klausen, Charlotte Vestrup Rift, Jane Preuss Hasselby, Anders Toxværd, Evangelos Kalaitzakis, Carsten Palnæs Hansen, Peter Vilmann

Abstract

Background and Objectives: Cystic lesions of the pancreas represent a diagnostic dilemma. Recently, a through-the-needle microbiopsy forceps has become available, enabling procurement of EUS-guided histological specimens from the pancreatic cyst wall. The aim of this study was to evaluate the use of this novel instrument in a multicenter clinical setting.

Patients and Methods: Patients referred for EUS evaluation of pancreatic cysts and attempted EUS-guided microbiopsy was included retrospectively from six international tertiary centers. Patient's demographics, EUS findings, technical and clinical success, and histopathological results were recorded.

Results: : A total of 28 patients were identified. We report a technical success rate of 85.7% (n = 24). Biopsies were generally of good quality and contributed to the diagnosis in 20 patients (clinical success of 71.4%). Three adverse events were recorded (10.7%).

Conclusions: The use of the microbiopsy forceps is feasible with acceptable rates of technical and clinical success. Prospective studies are warranted to determine the diagnostic potential compared to the other modalities. However, the results from this preliminary study are promising.

OriginalsprogEngelsk
TidsskriftEndoscopic Ultrasound
Vol/bind7
Udgave nummer6
Sider (fra-til)383-388
Antal sider6
ISSN2303-9027
DOI
StatusUdgivet - 1 sep. 2018

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