Inhalationsanæstetikas virkningsmekanismer

Helle Søholm; Niels Vidiendal Olsen

Inhalationsanæstetikas virkningsmekanismer

Helle Søholm, Niels Vidiendal Olsen

1 Citationer (Scopus)

Abstract

Anaesthesia is extensively used worldwide and in Denmark alone more than 400,000 anaesthesias are performed each year. In spite of that the molecularly mechanism of anaesthesia has not been proven. Hypotheses have been suggested (lipid versus protein theory), but none has yet been able to explain the whole mechanism. Molecular targets for volatile anaesthetics (e.g. potassium and calcium channels) affected areas in the central nervous system and the impact on the cerebral metabolism versus the cerebral blood flow are discussed.

Bidragets oversatte titel	Volatile anaesthesias' molecular biological course of action
Originalsprog	Dansk
Tidsskrift	Ugeskrift for Laeger
Vol/bind	175
Udgave nummer	3
Sider (fra-til)	123-7
Antal sider	5
ISSN	0041-5782
Status	Udgivet - 14 jan. 2013

Emneord

Anesthetics, Inhalation
Brain
Cerebrovascular Circulation
Humans
Ion Channels
Isoflurane
Methyl Ethers
Nitrous Oxide
Potassium Channels

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Link to publication in Scopus

Citationsformater

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abstract = "Anaesthesia is extensively used worldwide and in Denmark alone more than 400,000 anaesthesias are performed each year. In spite of that the molecularly mechanism of anaesthesia has not been proven. Hypotheses have been suggested (lipid versus protein theory), but none has yet been able to explain the whole mechanism. Molecular targets for volatile anaesthetics (e.g. potassium and calcium channels) affected areas in the central nervous system and the impact on the cerebral metabolism versus the cerebral blood flow are discussed.",

keywords = "Anesthetics, Inhalation, Brain, Cerebrovascular Circulation, Humans, Ion Channels, Isoflurane, Methyl Ethers, Nitrous Oxide, Potassium Channels",

author = "Helle S{\o}holm and Olsen, \{Niels Vidiendal\}",

year = "2013",

month = jan,

day = "14",

language = "Dansk",

volume = "175",

pages = "123--7",

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T1 - Inhalationsanæstetikas virkningsmekanismer

AU - Søholm, Helle

AU - Olsen, Niels Vidiendal

PY - 2013/1/14

Y1 - 2013/1/14

N2 - Anaesthesia is extensively used worldwide and in Denmark alone more than 400,000 anaesthesias are performed each year. In spite of that the molecularly mechanism of anaesthesia has not been proven. Hypotheses have been suggested (lipid versus protein theory), but none has yet been able to explain the whole mechanism. Molecular targets for volatile anaesthetics (e.g. potassium and calcium channels) affected areas in the central nervous system and the impact on the cerebral metabolism versus the cerebral blood flow are discussed.

AB - Anaesthesia is extensively used worldwide and in Denmark alone more than 400,000 anaesthesias are performed each year. In spite of that the molecularly mechanism of anaesthesia has not been proven. Hypotheses have been suggested (lipid versus protein theory), but none has yet been able to explain the whole mechanism. Molecular targets for volatile anaesthetics (e.g. potassium and calcium channels) affected areas in the central nervous system and the impact on the cerebral metabolism versus the cerebral blood flow are discussed.

KW - Anesthetics, Inhalation

KW - Brain

KW - Cerebrovascular Circulation

KW - Humans

KW - Ion Channels

KW - Isoflurane

KW - Methyl Ethers

KW - Nitrous Oxide

KW - Potassium Channels

UR - https://www.scopus.com/pages/publications/84872911667

M3 - Tidsskriftartikel

C2 - 23331943

SN - 0041-5782

VL - 175

SP - 123

EP - 127

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 3

ER -

Inhalationsanæstetikas virkningsmekanismer

Abstract

Emneord

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