Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index

Esther Zimmermann; Kristin Skogstrand; David M Hougaard; Arne Astrup; Torben Hansen; Oluf Borbye Pedersen; Thorkild I A Sørensen; Tine Jess

doi:10.1371/journal.pone.0015958

Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index

Esther Zimmermann, Kristin Skogstrand, David M Hougaard, Arne Astrup, Torben Hansen, Oluf Borbye Pedersen, Thorkild I A Sørensen, Tine Jess

37 Citationer (Scopus)

Abstract

A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish men.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	6
Udgave nummer	1
Sider (fra-til)	e15958
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0015958
Status	Udgivet - 2011

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abstract = "A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish men.",

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AU - Zimmermann, Esther

AU - Skogstrand, Kristin

AU - Hougaard, David M

AU - Astrup, Arne

AU - Hansen, Torben

AU - Pedersen, Oluf Borbye

AU - Sørensen, Thorkild I A

AU - Jess, Tine

PY - 2011

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N2 - A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish men.

AB - A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional circulating obesity-related adipokines throughout a broad range of body mass index (BMI) among Danish men.

KW - Adipokines

KW - Adult

KW - Aged

KW - Body Mass Index

KW - C-Reactive Protein

KW - Denmark

KW - Genetic Markers

KW - Genotype

KW - Humans

KW - Inflammation

KW - Male

KW - Middle Aged

KW - Obesity

KW - Polymorphism, Single Nucleotide

KW - Proteins

UR - https://www.scopus.com/pages/publications/79251575560

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DO - 10.1371/journal.pone.0015958

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SN - 1932-6203

VL - 6

SP - e15958

JO - P L o S One

JF - P L o S One

IS - 1

ER -

Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index

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