Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial

Peter Lommer Kristensen; Ulrik Pedersen-Bjergaard; Troels Wesenberg Kjær; Niels Vidiendal Olsen; Flemming Dela; Jens Juul Holst; Jens Faber; Lise Tarnow; Birger Thorsteinsson

doi:10.1371/journal.pone.0059672

Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial

Peter Lommer Kristensen, Ulrik Pedersen-Bjergaard, Troels Wesenberg Kjær, Niels Vidiendal Olsen, Flemming Dela, Jens Juul Holst, Jens Faber, Lise Tarnow, Birger Thorsteinsson

Afdeling for Hjerne- og Nerveundersøgelser NEU

19 Citationer (Scopus)

Abstract

The incidence of severe hypoglycemia in type 1 diabetes has not decreased over the past decades. New treatment modalities minimizing the risk of hypoglycemic episodes and attenuating hypoglycemic cognitive dysfunction are needed. We studied if treatment with the neuroprotective hormone erythropoietin (EPO) enhances cognitive function during hypoglycemia.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	8
Udgave nummer	4
Sider (fra-til)	e59672
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0059672
Status	Udgivet - 2013

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10.1371/journal.pone.0059672

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Kristensen, P. L., Pedersen-Bjergaard, U., Kjær, T. W., Olsen, N. V., Dela, F., Holst, J. J., Faber, J., Tarnow, L., & Thorsteinsson, B. (2013). Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial. P L o S One, 8(4), e59672. https://doi.org/10.1371/journal.pone.0059672

Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial. / Kristensen, Peter Lommer ; Pedersen-Bjergaard, Ulrik; Kjær, Troels Wesenberg et al.
I: P L o S One, Bind 8, Nr. 4, 2013, s. e59672.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Kristensen, PL , Pedersen-Bjergaard, U, Kjær, TW, Olsen, NV, Dela, F, Holst, JJ, Faber, J, Tarnow, L & Thorsteinsson, B 2013, 'Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial', P L o S One, bind 8, nr. 4, s. e59672. https://doi.org/10.1371/journal.pone.0059672

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abstract = "The incidence of severe hypoglycemia in type 1 diabetes has not decreased over the past decades. New treatment modalities minimizing the risk of hypoglycemic episodes and attenuating hypoglycemic cognitive dysfunction are needed. We studied if treatment with the neuroprotective hormone erythropoietin (EPO) enhances cognitive function during hypoglycemia.",

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AB - The incidence of severe hypoglycemia in type 1 diabetes has not decreased over the past decades. New treatment modalities minimizing the risk of hypoglycemic episodes and attenuating hypoglycemic cognitive dysfunction are needed. We studied if treatment with the neuroprotective hormone erythropoietin (EPO) enhances cognitive function during hypoglycemia.

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Influence of Erythropoietin on Cognitive Performance during Experimental Hypoglycemia in Patients with Type 1 Diabetes Mellitus: A Randomized Cross-Over Trial

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