Inflammation, coagulation and cardiovascular disease in HIV-infected individuals

Daniel A Duprez, Jacqueline Neuhaus, Lewis H Kuller, Russell Tracy, Waldo Belloso, Stephane De Wit, Fraser Drummond, H Clifford Lane, Bruno Ledergerber, Jens Lundgren, Daniel Nixon, Nicholas I Paton, Ronald J Prineas, James D Neaton, INSIGHT SMART Study Group

    430 Citationer (Scopus)

    Abstract

    The SMART study was a trial of intermittent use of antiretroviral therapy (ART) (drug conservation [DC]) versus continuous use of ART (viral suppression [VS]) as a strategy to reduce toxicities, including cardiovascular disease (CVD) risk. We studied the predictive value of high sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6) and D-dimer with CVD morbidity and mortality in HIV-infected patients who were enrolled in SMART beyond other measured CVD risk factors.
    OriginalsprogEngelsk
    TidsskriftP L o S One
    Vol/bind7
    Udgave nummer9
    Sider (fra-til)e44454
    ISSN1932-6203
    DOI
    StatusUdgivet - 2012

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