Inflammation Associates With Impaired Small Arterial Elasticity Early in HIV Disease

INSIGHT START (Strategic Timing of AntiRetroviral Treatment) Study Group

Abstract

We estimated small arterial elasticity and used linear regression to evaluate its association with inflammatory biomarkers among antiretroviral therapy-naïve, HIV-positive patients with high CD4+ counts. After adjustment, high-sensitivity C-reactive protein and interleukin-6 were inversely associated with small arterial elasticity. These data suggest that systemic inflammation may contribute to vascular dysfunction even in very early HIV disease.

OriginalsprogEngelsk
TidsskriftOpen Forum Infectious Diseases
Vol/bind5
Udgave nummer6
Sider (fra-til)ofy117
ISSN2328-8957
DOI
StatusUdgivet - 1 jun. 2018
Udgivet eksterntJa

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