Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Infective endocarditis in right ventricular outflow tract conduits: a register-based comparison of homografts, Contegra grafts and Melody transcatheter valves

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. 2019 EACTS Expert Consensus on long-term mechanical circulatory support

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Intraoperative flow profiles of arterial and venous bypass grafts to the left coronary territory

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Lung transplantation after ex vivo lung perfusion in two Scandinavian centres

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Burden and causes for hospitalizations following coronary artery bypass grafting: a nationwide cohort study†

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Vascular function in adults with cyanotic congenital heart disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Implications of hydrodynamic testing to guide sizing of self-expanding transcatheter heart valves for valve-in-valve procedures

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Performance of the TRUE dilatation balloon valvuloplasty catheter beyond rated burst pressure: A bench study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Early and late risk of ischemic stroke after TAVR as compared to a nationwide background population

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

OBJECTIVES: The aim was to investigate the incidence of infective endocarditis (IE) in right ventricle-to-pulmonary artery conduits implanted at a Danish tertiary centre.

METHODS: Cases of IE in patients with homografts, Contegra grafts and Melody transcatheter valves were evaluated retrospectively with regard to the likeliness of the diagnosis using the modified Duke criteria and the likeliness of conduit involvement. Incidence rates for IE were calculated 1 and 5 years after valve implantation for all 3 conduits, and separately for Melody subgroups depending on which conduit served as landing zone. Cox regression with time-dependent covariates was used to model the impact of the conduit type on the incidence of IE.

RESULTS: Annualized incidence rates of IE in homografts, Contegra grafts and Melody valves were 0.40% (0.40 cases per 100 patient-years), 0.97% and 6.96% 1 year and 0.27%, 1.12% and 2.89% 5 years after valve implantation. Hazard ratios (HRs) were 3.20 [95% confidence interval (CI) 0.91-11.17, P = 0.069] for Contegra grafts and 11.89 (95% CI 2.91-48.48, P < 0.001) for Melody valves compared to homografts.

CONCLUSIONS: Bovine pulmonary conduits were more prone to endocarditis, with Melody valves being the most frequently infected. HRs for the risk of suffering from endocarditis were substantially higher for Melody valves and Contegra grafts compared to homografts, although this finding was only statistically significant for Melody valves and not for Contegra grafts.

OriginalsprogEngelsk
TidsskriftEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Vol/bind56
Udgave nummer1
Sider (fra-til)87-93
Antal sider7
ISSN1010-7940
DOI
StatusUdgivet - 1 jul. 2019

Bibliografisk note

© The Author(s) 2019. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

ID: 59122741