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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Indomethacin lowers optic nerve oxygen tension and reduces the effect of carbonic anhydrase inhibition and carbon dioxide breathing

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Vis graf over relationer
Prostaglandins are important in blood flow regulation. Carbon dioxide (CO(2)) breathing and carbonic anhydrase inhibition increase the oxygen tension in the retina and optic nerve. To study the mechanism of this effect and the role of cyclo-oxygenase in the regulation of optic nerve oxygen tension (ONPO(2)), the authors investigated how indomethacin affects ONPO(2) and the ONPO(2) increases caused by CO(2) breathing and carbonic anhydrase inhibition in the pig.
OriginalsprogEngelsk
TidsskriftBritish Journal of Ophthalmology
Vol/bind88
Udgave nummer8
Sider (fra-til)1088-91
Antal sider4
ISSN0007-1161
DOI
StatusUdgivet - 2004

ID: 35960064