Indikationer for radioimmunterapi til patienter med non-Hodgkins lymfom

Ulf Christian Frølund, Per Boye Hansen

    Abstract

    Radioimmunotherapy is a well-known treatment for non-Hodgkin's lymphoma. (90)yttrium (Y)-ibritumomab-tiuxetan consists of a radioisotope conjugated to a monoclonal anti-cluster of differentiation 20 antibody, which is targeted against B-lymphocytes. Initially the treatment indication was relapse of low-grade non-Hodgkin's lymphoma. However, (90)Y-ibritumomab-tiuxetan has later been used in clinical trials in the treatment of other types of non-Hodgkin's lymphoma and prior to stem cell transplantation. Based on the literature this systematic review aims to throw light on the future possibilities of radioimmunotherapy.
    Bidragets oversatte titelIndications for radioimmunotherapy for patients with non-Hodgkin's lymphoma
    OriginalsprogDansk
    TidsskriftUgeskrift for Laeger
    Vol/bind173
    Udgave nummer20
    Sider (fra-til)1417-21
    Antal sider5
    ISSN0041-5782
    StatusUdgivet - 2011

    Emneord

    • Antibodies, Monoclonal
    • Humans
    • Lymphoma, Follicular
    • Lymphoma, Large B-Cell, Diffuse
    • Lymphoma, Mantle-Cell
    • Lymphoma, Non-Hodgkin
    • Neoplasm Recurrence, Local
    • Radioimmunotherapy
    • Stem Cell Transplantation
    • Treatment Outcome

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