Increased serum levels of interleukin-18 in patients with multiple sclerosis

F Nicoletti; R Di Marco; K Mangano; F Patti; E Reggio; A Nicoletti; K Bendtzen; A Reggio

Increased serum levels of interleukin-18 in patients with multiple sclerosis

F Nicoletti, R Di Marco, K Mangano, F Patti, E Reggio, A Nicoletti, K Bendtzen, A Reggio

84 Citationer (Scopus)

Abstract

Serum but not CSF concentrations of the interferon-gamma-inducing cytokine interleukin (IL)-18 were significantly augmented in patients with MS as compared to both healthy controls and patients with other neurologic diseases. Patients with MS with secondary chronic progressive disease had significantly higher serum levels than those with relapsing remitting MS. In the latter group, IL-18 levels were higher in patients with acute exacerbation as compared to those with stable disease.

Originalsprog	Engelsk
Tidsskrift	Neurology
Vol/bind	57
Udgave nummer	2
Sider (fra-til)	342-4
Antal sider	3
ISSN	0028-3878
Status	Udgivet - 24 jul. 2001

Citationsformater

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title = "Increased serum levels of interleukin-18 in patients with multiple sclerosis",

abstract = "Serum but not CSF concentrations of the interferon-gamma-inducing cytokine interleukin (IL)-18 were significantly augmented in patients with MS as compared to both healthy controls and patients with other neurologic diseases. Patients with MS with secondary chronic progressive disease had significantly higher serum levels than those with relapsing remitting MS. In the latter group, IL-18 levels were higher in patients with acute exacerbation as compared to those with stable disease.",

author = "F Nicoletti and {Di Marco}, R and K Mangano and F Patti and E Reggio and A Nicoletti and K Bendtzen and A Reggio",

year = "2001",

month = jul,

day = "24",

language = "English",

volume = "57",

pages = "342--4",

journal = "Neurology",

issn = "0028-3878",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Increased serum levels of interleukin-18 in patients with multiple sclerosis

AU - Nicoletti, F

AU - Di Marco, R

AU - Mangano, K

AU - Patti, F

AU - Reggio, E

AU - Nicoletti, A

AU - Bendtzen, K

AU - Reggio, A

PY - 2001/7/24

Y1 - 2001/7/24

N2 - Serum but not CSF concentrations of the interferon-gamma-inducing cytokine interleukin (IL)-18 were significantly augmented in patients with MS as compared to both healthy controls and patients with other neurologic diseases. Patients with MS with secondary chronic progressive disease had significantly higher serum levels than those with relapsing remitting MS. In the latter group, IL-18 levels were higher in patients with acute exacerbation as compared to those with stable disease.

AB - Serum but not CSF concentrations of the interferon-gamma-inducing cytokine interleukin (IL)-18 were significantly augmented in patients with MS as compared to both healthy controls and patients with other neurologic diseases. Patients with MS with secondary chronic progressive disease had significantly higher serum levels than those with relapsing remitting MS. In the latter group, IL-18 levels were higher in patients with acute exacerbation as compared to those with stable disease.

M3 - Journal article

C2 - 11468327

SN - 0028-3878

VL - 57

SP - 342

EP - 344

JO - Neurology

JF - Neurology

IS - 2

ER -

Increased serum levels of interleukin-18 in patients with multiple sclerosis

Abstract

Fingeraftryk

Citationsformater