Increased risk of abortion after genetic amniocentesis in twin pregnancies

C Palle, J W Andersen, A Tabor, J G Lauritsen, J Bang, J Philip

    49 Citationer (Scopus)

    Abstract

    Forty-seven twin pregnancies among 3676 patients who had a genetic amniocentesis between 1973 and 1979, are reported. The detection rate of twins at the time of amniocentesis was 62 per cent. Five (17 per cent) of the 29 women with detected twin pregnancy aborted spontaneously, these are compared with 1 (6 per cent) of 18 women with undetected twin pregnancies and with 3 (3 per cent) of 93 singleton pregnancies, selected as controls as they had amniocentesis performed immediately before and after each of the twin mothers. Two of 9 (22 per cent) twin pregnancies, who had at least two punctures in at least one sac aborted, while 3 of 20 twin pregnancies with one puncture in each sac aborted (15 per cent). One of 18 (6 per cent) twin pregnancies, where only one sac was punctured, because the twin pregnancies were undetected, aborted. Amniocentesis of both sacs in twin pregnancies seems associated with an increased risk of spontaneous abortion. The indications for amniocentesis in twin pregnancies should be critically evaluated.

    OriginalsprogEngelsk
    TidsskriftPrenatal Diagnosis
    Vol/bind3
    Udgave nummer2
    Sider (fra-til)83-9
    Antal sider7
    ISSN0197-3851
    StatusUdgivet - 1 apr. 1983

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