Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects

Katrine Bagge  Hansen; Tina Vilsbøll; Jonatan I Bagger; Jens Juul Holst; Filip K Knop

doi:10.1210/jc.2010-1605

Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects

Katrine Bagge Hansen, Tina Vilsbøll, Jonatan I Bagger, Jens Juul Holst, Filip K Knop

Afdeling for Klinisk Fysiologi og Nuklearmedicin

40 Citationer (Scopus)

Abstract

Increased postprandial glucose-dependent insulinotropic polypeptide (GIP) and glucagon responses and reduced postprandial glucagon-like peptide-1 (GLP-1) responses have been observed in some patients with type 2 diabetes mellitus. The causality of these pathophysiological traits is unknown. We aimed to determine the impact of insulin resistance and reduced glucose tolerance on postprandial GIP, GLP-1, and glucagon responses in healthy subjects.

Originalsprog	Engelsk
Tidsskrift	The Journal of clinical endocrinology and metabolism
Vol/bind	96
Udgave nummer	2
Sider (fra-til)	447-53
Antal sider	7
DOI	https://doi.org/10.1210/jc.2010-1605
Status	Udgivet - 1 feb. 2011

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10.1210/jc.2010-1605

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Hansen, K. B., Vilsbøll, T., Bagger, J. I., Holst, J. J., & Knop, F. K. (2011). Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects. The Journal of clinical endocrinology and metabolism, 96(2), 447-53. https://doi.org/10.1210/jc.2010-1605

Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects. / Hansen, Katrine Bagge ; Vilsbøll, Tina ; Bagger, Jonatan I et al.
I: The Journal of clinical endocrinology and metabolism, Bind 96, Nr. 2, 01.02.2011, s. 447-53.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Hansen, KB , Vilsbøll, T , Bagger, JI, Holst, JJ & Knop, FK 2011, 'Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects', The Journal of clinical endocrinology and metabolism, bind 96, nr. 2, s. 447-53. https://doi.org/10.1210/jc.2010-1605

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abstract = "Increased postprandial glucose-dependent insulinotropic polypeptide (GIP) and glucagon responses and reduced postprandial glucagon-like peptide-1 (GLP-1) responses have been observed in some patients with type 2 diabetes mellitus. The causality of these pathophysiological traits is unknown. We aimed to determine the impact of insulin resistance and reduced glucose tolerance on postprandial GIP, GLP-1, and glucagon responses in healthy subjects.",

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AU - Knop, Filip K

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Increased postprandial GIP and glucagon responses, but unaltered GLP-1 response after intervention with steroid hormone, relative physical inactivity, and high-calorie diet in healthy subjects

Abstract

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