Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica

Frederik Kreiner; Henning Langberg Jørgensen; Henrik Galbo

doi:10.1002/art.27728

Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica

Frederik Kreiner, Henning Langberg Jørgensen, Henrik Galbo

Ortopædkirurgisk Afdeling M

62 Citationer (Scopus)

Abstract

Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.

Originalsprog	Engelsk
Tidsskrift	Arthritis & Rheumatism
Vol/bind	62
Udgave nummer	12
Sider (fra-til)	3768-75
Antal sider	8
ISSN	0004-3591
DOI	https://doi.org/10.1002/art.27728
Status	Udgivet - 1 dec. 2010

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10.1002/art.27728

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title = "Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica",

abstract = "Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.",

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AU - Kreiner, Frederik

AU - Jørgensen, Henning Langberg

AU - Galbo, Henrik

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N2 - Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.

AB - Polymyalgia rheumatica (PMR) is characterized by aching of the proximal muscles and increased blood levels of markers of inflammation. Despite the muscle complaints, the current view is that symptoms are caused by inflammation in synovial structures. The purpose of this study was to elucidate the disease mechanisms in symptomatic muscles by measuring interstitial levels of cytokines before and after prednisolone treatment.

U2 - 10.1002/art.27728

DO - 10.1002/art.27728

M3 - Journal article

C2 - 20812339

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EP - 3775

JO - Arthritis & Rheumatism

JF - Arthritis & Rheumatism

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ER -

Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica

Abstract

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