Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria

Kåre Kemp; Jørgen A L Kurtzhals; Bartholomew D Akanmori; Victoria Adabayeri; Bamenla Q Goka; Charlotte Behr; Lars Hviid

doi:10.1128/cdli.9.3.720-722.2002

Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria

Kåre Kemp, Jørgen A L Kurtzhals, Bartholomew D Akanmori, Victoria Adabayeri, Bamenla Q Goka, Charlotte Behr, Lars Hviid

4 Citationer (Scopus)

Abstract

Levels of soluble CD30 (sCD30) in serum were elevated in patients with Plasmodium falciparum malaria but showed decline following treatment. The levels of sCD30 in serum were correlated significantly with the expression of gamma interferon by peripheral T cells. These data suggest that CD30(+) cells are upregulated during a malaria attack and that they may play a regulating role at the site of inflammation.

Originalsprog	Engelsk
Tidsskrift	Clinical and Diagnostic Laboratory Immunology
Vol/bind	9
Udgave nummer	3
Sider (fra-til)	720-2
Antal sider	3
ISSN	1071-412X
DOI	https://doi.org/10.1128/cdli.9.3.720-722.2002
Status	Udgivet - maj 2002
Udgivet eksternt	Ja

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10.1128/cdli.9.3.720-722.2002

Citationsformater

@article{4354447293864fa484a9e8bc41323b56,

title = "Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria",

abstract = "Levels of soluble CD30 (sCD30) in serum were elevated in patients with Plasmodium falciparum malaria but showed decline following treatment. The levels of sCD30 in serum were correlated significantly with the expression of gamma interferon by peripheral T cells. These data suggest that CD30(+) cells are upregulated during a malaria attack and that they may play a regulating role at the site of inflammation.",

keywords = "Animals, Cells, Cultured, Child, Ghana, Humans, Interferon-gamma/biosynthesis, Ki-1 Antigen/blood, Malaria, Falciparum/blood, Plasmodium falciparum/immunology, Solubility, T-Lymphocytes/cytology",

author = "K{\aa}re Kemp and Kurtzhals, {J{\o}rgen A L} and Akanmori, {Bartholomew D} and Victoria Adabayeri and Goka, {Bamenla Q} and Charlotte Behr and Lars Hviid",

year = "2002",

month = may,

doi = "10.1128/cdli.9.3.720-722.2002",

language = "English",

volume = "9",

pages = "720--2",

journal = "Clinical and Diagnostic Laboratory Immunology",

issn = "1071-412X",

publisher = "American Society for Microbiology",

number = "3",

}

TY - JOUR

T1 - Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria

AU - Kemp, Kåre

AU - Kurtzhals, Jørgen A L

AU - Akanmori, Bartholomew D

AU - Adabayeri, Victoria

AU - Goka, Bamenla Q

AU - Behr, Charlotte

AU - Hviid, Lars

PY - 2002/5

Y1 - 2002/5

N2 - Levels of soluble CD30 (sCD30) in serum were elevated in patients with Plasmodium falciparum malaria but showed decline following treatment. The levels of sCD30 in serum were correlated significantly with the expression of gamma interferon by peripheral T cells. These data suggest that CD30(+) cells are upregulated during a malaria attack and that they may play a regulating role at the site of inflammation.

AB - Levels of soluble CD30 (sCD30) in serum were elevated in patients with Plasmodium falciparum malaria but showed decline following treatment. The levels of sCD30 in serum were correlated significantly with the expression of gamma interferon by peripheral T cells. These data suggest that CD30(+) cells are upregulated during a malaria attack and that they may play a regulating role at the site of inflammation.

KW - Animals

KW - Cells, Cultured

KW - Child

KW - Ghana

KW - Humans

KW - Interferon-gamma/biosynthesis

KW - Ki-1 Antigen/blood

KW - Malaria, Falciparum/blood

KW - Plasmodium falciparum/immunology

KW - Solubility

KW - T-Lymphocytes/cytology

U2 - 10.1128/cdli.9.3.720-722.2002

DO - 10.1128/cdli.9.3.720-722.2002

M3 - Journal article

C2 - 11986285

SN - 1071-412X

VL - 9

SP - 720

EP - 722

JO - Clinical and Diagnostic Laboratory Immunology

JF - Clinical and Diagnostic Laboratory Immunology

IS - 3

ER -

Increased levels of soluble CD30 in plasma of patients with Plasmodium falciparum malaria

Abstract

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