Increased cocaine self-administration in M4 muscarinic acetylcholine receptor knockout mice

Lene Skytthe Kaarsberg Schmidt, Morgane Thomsen, Pia Weikop, Ditte Dencker Nielsen, Jürgen Wess, David P D Woldbye, Gitta Wörtwein, Anders Fink-Jensen

    58 Citationer (Scopus)

    Abstrakt

    The reinforcing effects of cocaine are mediated by the mesolimbic dopamine system. Behavioral and neurochemical studies have shown that the cholinergic muscarinic M(4) receptor subtype plays an important role in regulation of dopaminergic neurotransmission.
    OriginalsprogEngelsk
    TidsskriftPsychopharmacology
    Vol/bind216
    Udgave nummer3
    Sider (fra-til)367-78
    Antal sider12
    ISSN0033-3158
    DOI
    StatusUdgivet - 2011

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