TY - JOUR
T1 - Incidence of diabetic eye disease among migrants
T2 - a cohort study of 100,000 adults with diabetes in Denmark
AU - Oya, Junko
AU - Jørgensen, Marit Eika
AU - Lund-Andersen, Henrik
AU - Carstensen, Bendix
AU - Andersen, Gregers Stig
N1 - Copyright © 2018. Published by Elsevier B.V.
PY - 2018/10
Y1 - 2018/10
N2 - AIMS: To examine the incidence rates of any and referable diabetic retinopathy (DR) in Denmark among migrants.METHODS: Nationwide clinical data on diabetes patients followed since 2005. Patients were classified according to country of origin into six groups: Denmark, other Europe, Sub Saharan Africa, Middle East/-North Africa, Asia, and America. 93,780 or 110,897 patients without any (include unspecific diagnoses) or referable (proliferative) DR at baseline were analyzed. We estimated event rates and hazard ratios (HRs) for incidence of any- and referable DR according to country of origin.RESULTS: After an average follow-up of 3.59 years 6,727 had incident any DR and 4,747 patients had referable DR. Compared to Danish, migrants from the Middle East/-North Africa and Asia had a higher risk of any and referable DR after adjustment for age, sex, body mass index, smoking status, types and duration of diabetes, HbA1c, study center, blood pressure and lipid levels. The associations remained significant after further adjustment for frequency of eye screening.CONCLUSIONS: Migrants from the Middle East/-North Africa and Asia showed higher risk of incidence of any and referable DR compared to Danish, and these differences were not fully explained by differences in underlying clinical, diabetic and cardiometabolic risk factors.
AB - AIMS: To examine the incidence rates of any and referable diabetic retinopathy (DR) in Denmark among migrants.METHODS: Nationwide clinical data on diabetes patients followed since 2005. Patients were classified according to country of origin into six groups: Denmark, other Europe, Sub Saharan Africa, Middle East/-North Africa, Asia, and America. 93,780 or 110,897 patients without any (include unspecific diagnoses) or referable (proliferative) DR at baseline were analyzed. We estimated event rates and hazard ratios (HRs) for incidence of any- and referable DR according to country of origin.RESULTS: After an average follow-up of 3.59 years 6,727 had incident any DR and 4,747 patients had referable DR. Compared to Danish, migrants from the Middle East/-North Africa and Asia had a higher risk of any and referable DR after adjustment for age, sex, body mass index, smoking status, types and duration of diabetes, HbA1c, study center, blood pressure and lipid levels. The associations remained significant after further adjustment for frequency of eye screening.CONCLUSIONS: Migrants from the Middle East/-North Africa and Asia showed higher risk of incidence of any and referable DR compared to Danish, and these differences were not fully explained by differences in underlying clinical, diabetic and cardiometabolic risk factors.
U2 - 10.1016/j.diabres.2018.08.021
DO - 10.1016/j.diabres.2018.08.021
M3 - Journal article
C2 - 30213771
SN - 0168-8227
VL - 144
SP - 224
EP - 230
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
ER -