In vivo 1H spectroscopy of the human brain at 1.5 tesla. Preliminary experience at a clinical installation.

Bidragets oversatte titel: In vivo 1H spectroscopy of the human brain at 1.5 tesla. Preliminary experience at a clinical installation.

O Henriksen, H Larsson, K M Jensen

13 Citationer (Scopus)

Abstract

In vivo localized water suppressed proton spectroscopy of human brain was carried out on 15 healthy volunteers and 2 patients suffering from a brain tumour and an infarction, respectively. The measurements were performed on a whole body MR system, operating at 1.5 tesla using the stimulated echo technique. Our preliminary results indicate that it is possible to detect a number of metabolites in the brain within a total measurement time of one hour. The dominant peaks in the spectra from healthy volunteers are N-acetyl aspartate, choline and creatine/phosphocreatine. The spectra obtained from the brain tumour and the infarct, respectively, differed very much from those obtained in healthy brain tissue. Our preliminary results indicate that localized proton spectroscopy may contribute to non-invasive brain tumour classification and possibly also to the differentiation between tumours and infarcts in clinically doubtful cases.
Bidragets oversatte titelIn vivo 1H spectroscopy of the human brain at 1.5 tesla. Preliminary experience at a clinical installation.
OriginalsprogEngelsk
TidsskriftActa Radiologica
Vol/bind31
Udgave nummer2
Sider (fra-til)181-186
Antal sider6
ISSN0284-1851
StatusUdgivet - 1990

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