In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia

Gudmar Lönnerholm, Ingrid Thörn, Christer Sundström, Britt-Marie Frost, Trond Flaegstad, Mats Heyman, Olafur Gisli Jonsson, Arja Harila-Saari, Hans O Madsen, Anna Porwit, Kjeld Schmiegelow, Stefan Söderhäll, Finn Wesenberg, Kim Vettenranta, Rolf Larsson, Erik Forestier

8 Citationer (Scopus)

Abstract

Leukemic cells from 230 children with newly diagnosed B-cell precursor ALL were tested for in vitro drug resistance to a panel of anti-cancer drugs. Minimal residual disease (MRD) was measured by RQ-PCR. During follow-up, 24 relapses occurred in the 159 children with MRD
OriginalsprogEngelsk
TidsskriftLeukemia Research
Vol/bind35
Udgave nummer4
Sider (fra-til)472-8
Antal sider7
ISSN0261-474X
DOI
StatusUdgivet - 2011

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