Impotens forårsaget af behandling med methotrexat

Elisabeth I Penninga, Helle Kiellberg Larsen, Stig Ejdrup Andersen


Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.

Bidragets oversatte titelImpotence caused by Methotrexate treatment
TidsskriftUgeskrift for Laeger
Udgave nummer5
Sider (fra-til)354
StatusUdgivet - 28 jan. 2008


  • Dermatitis, Exfoliative/drug therapy
  • Dermatologic Agents/adverse effects
  • Erectile Dysfunction/chemically induced
  • Humans
  • Male
  • Methotrexate/adverse effects
  • Middle Aged


Dyk ned i forskningsemnerne om 'Impotens forårsaget af behandling med methotrexat'. Sammen danner de et unikt fingeraftryk.