Impotens forårsaget af behandling med methotrexat

Elisabeth I Penninga, Helle Kiellberg Larsen, Stig Ejdrup Andersen

Abstract

Methotrexate (MTX) is used in the treatment of malignant and non-malignant diseases. This case report describes impotence as a seldom but possible overlooked adverse effect to MTX treatment. A 58 year-old man was treated for erythrodermia with a weekly dose of 7.5 mg MTX. He developed erective impotence nine months after initiation of treatment. Two weeks after discontinuation of MTX the impotence subsided, but when MTX treatment was reintroduced, the impotence returned after two months. Only a few other cases of impotence associated with MTX have been described previously.

Bidragets oversatte titelImpotence caused by Methotrexate treatment
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind170
Udgave nummer5
Sider (fra-til)354
ISSN0041-5782
StatusUdgivet - 28 jan. 2008

Emneord

  • Dermatitis, Exfoliative/drug therapy
  • Dermatologic Agents/adverse effects
  • Erectile Dysfunction/chemically induced
  • Humans
  • Male
  • Methotrexate/adverse effects
  • Middle Aged

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