Imported leishmaniasis in Denmark

Mike Zangenberg; Marie Helleberg; Christen Rune Stensvold; Henrik Vedel Nielsen

doi:10.61409/V09230568

Imported leishmaniasis in Denmark

Mike Zangenberg, Marie Helleberg, Christen Rune Stensvold, Henrik Vedel Nielsen

Abstract

Leishmaniasis is transmitted by sandflies and involves cutaneous, mucocutaneous, or visceral disease. Sporadic, imported cases in Denmark emphasize the need for greater awareness. The incidence is stable with at least ten verified cases per year. Diagnostic methods include PCR- and antibody tests with a high positivity rate for PCR (17%) and a low positivity rate for antibody (1.4%). The latter should be used only when visceral disease is suspected. Immunosuppressed patients are at particular risk. Treatment strategies are chosen according to the severity of the condition, as argued in this review.

Bidragets oversatte titel	Imported leishmaniasis in Denmark
Originalsprog	Dansk
Artikelnummer	V09230568
Tidsskrift	Ugeskrift for Laeger
Vol/bind	186
Udgave nummer	17
ISSN	0041-5782
DOI	https://doi.org/10.61409/V09230568
Status	Udgivet - 22 apr. 2024

Emneord

Humans
Denmark/epidemiology
Leishmaniasis/diagnosis
Communicable Diseases, Imported/diagnosis
Antiprotozoal Agents/therapeutic use
Polymerase Chain Reaction
Leishmaniasis, Cutaneous/diagnosis

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10.61409/V09230568Licens: CC BY

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https://ugeskriftet.dk/videnskab/importeret-leishmaniasis

Citationsformater

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title = "Imported leishmaniasis in Denmark",

abstract = "Leishmaniasis is transmitted by sandflies and involves cutaneous, mucocutaneous, or visceral disease. Sporadic, imported cases in Denmark emphasize the need for greater awareness. The incidence is stable with at least ten verified cases per year. Diagnostic methods include PCR- and antibody tests with a high positivity rate for PCR (17%) and a low positivity rate for antibody (1.4%). The latter should be used only when visceral disease is suspected. Immunosuppressed patients are at particular risk. Treatment strategies are chosen according to the severity of the condition, as argued in this review.",

keywords = "Humans, Denmark/epidemiology, Leishmaniasis/diagnosis, Communicable Diseases, Imported/diagnosis, Antiprotozoal Agents/therapeutic use, Polymerase Chain Reaction, Leishmaniasis, Cutaneous/diagnosis",

author = "Mike Zangenberg and Marie Helleberg and Stensvold, {Christen Rune} and Nielsen, {Henrik Vedel}",

note = "Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.",

year = "2024",

month = apr,

day = "22",

doi = "10.61409/V09230568",

language = "Dansk",

volume = "186",

journal = "Ugeskrift for Laeger",

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T1 - Imported leishmaniasis in Denmark

AU - Zangenberg, Mike

AU - Helleberg, Marie

AU - Stensvold, Christen Rune

AU - Nielsen, Henrik Vedel

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2024/4/22

Y1 - 2024/4/22

N2 - Leishmaniasis is transmitted by sandflies and involves cutaneous, mucocutaneous, or visceral disease. Sporadic, imported cases in Denmark emphasize the need for greater awareness. The incidence is stable with at least ten verified cases per year. Diagnostic methods include PCR- and antibody tests with a high positivity rate for PCR (17%) and a low positivity rate for antibody (1.4%). The latter should be used only when visceral disease is suspected. Immunosuppressed patients are at particular risk. Treatment strategies are chosen according to the severity of the condition, as argued in this review.

AB - Leishmaniasis is transmitted by sandflies and involves cutaneous, mucocutaneous, or visceral disease. Sporadic, imported cases in Denmark emphasize the need for greater awareness. The incidence is stable with at least ten verified cases per year. Diagnostic methods include PCR- and antibody tests with a high positivity rate for PCR (17%) and a low positivity rate for antibody (1.4%). The latter should be used only when visceral disease is suspected. Immunosuppressed patients are at particular risk. Treatment strategies are chosen according to the severity of the condition, as argued in this review.

KW - Humans

KW - Denmark/epidemiology

KW - Leishmaniasis/diagnosis

KW - Communicable Diseases, Imported/diagnosis

KW - Antiprotozoal Agents/therapeutic use

KW - Polymerase Chain Reaction

KW - Leishmaniasis, Cutaneous/diagnosis

UR - https://ugeskriftet.dk/videnskab/importeret-leishmaniasis

U2 - 10.61409/V09230568

DO - 10.61409/V09230568

M3 - Review

C2 - 38704708

SN - 0041-5782

VL - 186

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 17

M1 - V09230568

ER -

Imported leishmaniasis in Denmark

Abstract

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