Impaired regulation of the incretin effect in patients with type 2 diabetes

Jonatan I Bagger; Filip K Knop; Asger Lund; Henrik Vestergaard; Jens Juul Holst; Tina Vilsbøll

doi:10.1210/jc.2010-2435

Impaired regulation of the incretin effect in patients with type 2 diabetes

Jonatan I Bagger, Filip K Knop, Asger Lund, Henrik Vestergaard, Jens Juul Holst, Tina Vilsbøll

189 Citationer (Scopus)

Abstract

In healthy subjects, the incretin effect during an oral glucose tolerance test increases with the size of glucose load, resulting in similar glucose excursions independently of the glucose loads. Whether patients with type 2 diabetes mellitus (T2DM) are able to regulate their incretin effect is unknown.

Originalsprog	Engelsk
Tidsskrift	The Journal of clinical endocrinology and metabolism
Vol/bind	96
Udgave nummer	3
Sider (fra-til)	737-45
Antal sider	9
DOI	https://doi.org/10.1210/jc.2010-2435
Status	Udgivet - 1 mar. 2011

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10.1210/jc.2010-2435

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title = "Impaired regulation of the incretin effect in patients with type 2 diabetes",

abstract = "In healthy subjects, the incretin effect during an oral glucose tolerance test increases with the size of glucose load, resulting in similar glucose excursions independently of the glucose loads. Whether patients with type 2 diabetes mellitus (T2DM) are able to regulate their incretin effect is unknown.",

author = "Bagger, {Jonatan I} and Knop, {Filip K} and Asger Lund and Henrik Vestergaard and Holst, {Jens Juul} and Tina Vilsb{\o}ll",

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AU - Knop, Filip K

AU - Lund, Asger

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AU - Vilsbøll, Tina

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N2 - In healthy subjects, the incretin effect during an oral glucose tolerance test increases with the size of glucose load, resulting in similar glucose excursions independently of the glucose loads. Whether patients with type 2 diabetes mellitus (T2DM) are able to regulate their incretin effect is unknown.

AB - In healthy subjects, the incretin effect during an oral glucose tolerance test increases with the size of glucose load, resulting in similar glucose excursions independently of the glucose loads. Whether patients with type 2 diabetes mellitus (T2DM) are able to regulate their incretin effect is unknown.

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DO - 10.1210/jc.2010-2435

M3 - Journal article

C2 - 21252240

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JO - The Journal of clinical endocrinology and metabolism

JF - The Journal of clinical endocrinology and metabolism

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ER -

Impaired regulation of the incretin effect in patients with type 2 diabetes

Abstract

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