Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Impaired physical function, loss of muscle mass and assessment of biomechanical properties in critical ill patients

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Trends of ankyloglossia and lingual frenotomy in hospital settings among children in Denmark

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Distribution of risk alleles in patients with age-related macular degeneration

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Outcomes and follow-up programmes in extreme preterm children in Denmark in the EPICE/SHIPS cohort

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Risk of pancreatitis in patients with inflammatory bowel disease - a meta-analysis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Danish expanded newborn screening is a successful preventive public health programme

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. High-Quality Exome Sequencing of Whole-Genome Amplified Neonatal Dried Blood Spot DNA

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. A Novel Noninvasive Method for Measuring Fatigability of the Quadriceps Muscle in Noncooperating Healthy Subjects

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Biomechanical and nonfunctional assessment of physical capacity in male ICU survivors

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Impaired physical function, loss of muscle mass and assessment of contractile properties in critically ill patients

    Publikation: Bog/antologi/afhandling/rapportPh.d.-afhandlingForskning

Vis graf over relationer

Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report sustained limitation of physical capacity for years after discharge. Limited information is available on the underlying biomechanical properties responsible for this muscle function impairment. A plausible contributor to the accentuated catabolic drive in ICU patients is a synergistic response to inflammation and inactivity leading to loss of muscle mass. As these entities are predominantly present in the early phase of ICU stay, interventions employed during this time frame may exhibit the greatest potential to counteract loss of muscle mass. Despite the obvious clinical significance of muscle atrophy for the functional impairment observed in ICU survivors, no preventive therapies have been identified as yet. The overall aim of the present dissertation is to characterize aspects of physical function and biomechanical properties in ICU patients and to provide new insights into ICU-induced muscle wasting and the underlying biomechanical mechanisms responsible for the residual impairment of physical function in ICU survivors.

OriginalsprogEngelsk
TidsskriftDanish Medical Bulletin (Online)
Vol/bind59
Udgave nummer11
Sider (fra-til)B4544
ISSN1603-9629
StatusUdgivet - nov. 2012

ID: 44888334