Impaired awareness of deficits and neuropsychiatric symptoms in early Alzheimer's disease: the Danish Alzheimer Intervention Study (DAISY)

Asmus Vogel, Frans Boch Waldorff, Gunhild Waldemar

35 Citationer (Scopus)

Abstract

Impaired awareness may be associated with increased neuropsychiatric symptoms in moderate to severe Alzheimer's disease, but relatively little is known about the association in early Alzheimer's disease. The aim of this study was to investigate if impaired awareness was associated with a higher frequency of neuropsychiatric symptoms in early Alzheimer's disease. In a Danish multicenter study, 321 patients with MMSE score > or =20 were evaluated. Patients with poor insight had significantly more neuropsychiatric symptoms than patients with full insight. When patients had increasing neuropsychiatric symptoms, caregivers reported higher levels of distress.
OriginalsprogEngelsk
TidsskriftThe Journal of neuropsychiatry and clinical neurosciences
Vol/bind22
Udgave nummer1
Sider (fra-til)93-9
Antal sider7
DOI
StatusUdgivet - 1 jan. 2010

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