Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry

Jakob Ledwoch; Jennifer Franke; Stephan Baldus; Wolfgang Schillinger; Raffi Bekeredjian; Peter Boekstegers; Ulrich Hink; Karl-Heinz Kuck; Taoufik Ouarrak; Helge Möllmann; Georg Nickenig; Jochen Senges; Olaf Franzen; Horst Sievert

doi:10.1007/s00392-014-0734-y

Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry

Jakob Ledwoch, Jennifer Franke, Stephan Baldus, Wolfgang Schillinger, Raffi Bekeredjian, Peter Boekstegers, Ulrich Hink, Karl-Heinz Kuck, Taoufik Ouarrak, Helge Möllmann, Georg Nickenig, Jochen Senges, Olaf Franzen, Horst Sievert

19 Citationer (Scopus)

Abstract

AIMS: This analysis from the German Mitral Valve Registry investigates the impact of the learning curve with the MitraClip(®) technique on procedural success and complications.

METHODS AND RESULTS: Consecutive patients treated since 2009 in centers that performed more than 50 transcatheter mitral repairs were included. Results of the first half of the patients were compared to those of the second. Altogether 496 patients from 10 centers were included. Patients treated later had less common severe heart failure symptoms (patients with NYHA IV: 22.1 vs. 14.5 %, p < 0.05). The EuroSCORE I (22.0 vs. 23.0 %, p = ns) and Society of Thoracic Surgeons (STS) score (7.5 vs. 9.5 %, p = ns) did not differ between both groups. Procedural success was 95.6 % (238/249) in the first cases and 94.7 % (232/245, p = ns) subsequently. Also procedural time (104.3 vs. 119 min, p = ns) and complications did not decrease over time.

CONCLUSION: A learning curve using the MitraClip(®) device does not appear to significantly affect acute MR reduction, hospital and 30-day mortality. Most likely, the proctor system leads to already high initial procedure success and relatively short procedure time.

Originalsprog	Engelsk
Tidsskrift	Clinical research in cardiology : official journal of the German Cardiac Society
Vol/bind	103
Udgave nummer	11
Sider (fra-til)	930-7
Antal sider	8
ISSN	1861-0684
DOI	https://doi.org/10.1007/s00392-014-0734-y
Status	Udgivet - nov. 2014

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10.1007/s00392-014-0734-y

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Ledwoch, J., Franke, J., Baldus, S., Schillinger, W., Bekeredjian, R., Boekstegers, P., Hink, U., Kuck, K.-H., Ouarrak, T., Möllmann, H., Nickenig, G., Senges, J., Franzen, O., & Sievert, H. (2014). Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry. Clinical research in cardiology : official journal of the German Cardiac Society, 103(11), 930-7. https://doi.org/10.1007/s00392-014-0734-y

Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry. / Ledwoch, Jakob; Franke, Jennifer; Baldus, Stephan et al.
I: Clinical research in cardiology : official journal of the German Cardiac Society, Bind 103, Nr. 11, 11.2014, s. 930-7.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Ledwoch, J, Franke, J, Baldus, S, Schillinger, W, Bekeredjian, R, Boekstegers, P, Hink, U, Kuck, K-H, Ouarrak, T, Möllmann, H, Nickenig, G, Senges, J, Franzen, O & Sievert, H 2014, 'Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry', Clinical research in cardiology : official journal of the German Cardiac Society, bind 103, nr. 11, s. 930-7. https://doi.org/10.1007/s00392-014-0734-y

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abstract = "AIMS: This analysis from the German Mitral Valve Registry investigates the impact of the learning curve with the MitraClip({\textregistered}) technique on procedural success and complications.METHODS AND RESULTS: Consecutive patients treated since 2009 in centers that performed more than 50 transcatheter mitral repairs were included. Results of the first half of the patients were compared to those of the second. Altogether 496 patients from 10 centers were included. Patients treated later had less common severe heart failure symptoms (patients with NYHA IV: 22.1 vs. 14.5 %, p < 0.05). The EuroSCORE I (22.0 vs. 23.0 %, p = ns) and Society of Thoracic Surgeons (STS) score (7.5 vs. 9.5 %, p = ns) did not differ between both groups. Procedural success was 95.6 % (238/249) in the first cases and 94.7 % (232/245, p = ns) subsequently. Also procedural time (104.3 vs. 119 min, p = ns) and complications did not decrease over time.CONCLUSION: A learning curve using the MitraClip({\textregistered}) device does not appear to significantly affect acute MR reduction, hospital and 30-day mortality. Most likely, the proctor system leads to already high initial procedure success and relatively short procedure time.",

author = "Jakob Ledwoch and Jennifer Franke and Stephan Baldus and Wolfgang Schillinger and Raffi Bekeredjian and Peter Boekstegers and Ulrich Hink and Karl-Heinz Kuck and Taoufik Ouarrak and Helge M{\"o}llmann and Georg Nickenig and Jochen Senges and Olaf Franzen and Horst Sievert",

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doi = "10.1007/s00392-014-0734-y",

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T1 - Impact of the learning curve on outcome after transcatheter mitral valve repair

T2 - results from the German Mitral Valve Registry

AU - Ledwoch, Jakob

AU - Franke, Jennifer

AU - Baldus, Stephan

AU - Schillinger, Wolfgang

AU - Bekeredjian, Raffi

AU - Boekstegers, Peter

AU - Hink, Ulrich

AU - Kuck, Karl-Heinz

AU - Ouarrak, Taoufik

AU - Möllmann, Helge

AU - Nickenig, Georg

AU - Senges, Jochen

AU - Franzen, Olaf

AU - Sievert, Horst

PY - 2014/11

Y1 - 2014/11

N2 - AIMS: This analysis from the German Mitral Valve Registry investigates the impact of the learning curve with the MitraClip(®) technique on procedural success and complications.METHODS AND RESULTS: Consecutive patients treated since 2009 in centers that performed more than 50 transcatheter mitral repairs were included. Results of the first half of the patients were compared to those of the second. Altogether 496 patients from 10 centers were included. Patients treated later had less common severe heart failure symptoms (patients with NYHA IV: 22.1 vs. 14.5 %, p < 0.05). The EuroSCORE I (22.0 vs. 23.0 %, p = ns) and Society of Thoracic Surgeons (STS) score (7.5 vs. 9.5 %, p = ns) did not differ between both groups. Procedural success was 95.6 % (238/249) in the first cases and 94.7 % (232/245, p = ns) subsequently. Also procedural time (104.3 vs. 119 min, p = ns) and complications did not decrease over time.CONCLUSION: A learning curve using the MitraClip(®) device does not appear to significantly affect acute MR reduction, hospital and 30-day mortality. Most likely, the proctor system leads to already high initial procedure success and relatively short procedure time.

AB - AIMS: This analysis from the German Mitral Valve Registry investigates the impact of the learning curve with the MitraClip(®) technique on procedural success and complications.METHODS AND RESULTS: Consecutive patients treated since 2009 in centers that performed more than 50 transcatheter mitral repairs were included. Results of the first half of the patients were compared to those of the second. Altogether 496 patients from 10 centers were included. Patients treated later had less common severe heart failure symptoms (patients with NYHA IV: 22.1 vs. 14.5 %, p < 0.05). The EuroSCORE I (22.0 vs. 23.0 %, p = ns) and Society of Thoracic Surgeons (STS) score (7.5 vs. 9.5 %, p = ns) did not differ between both groups. Procedural success was 95.6 % (238/249) in the first cases and 94.7 % (232/245, p = ns) subsequently. Also procedural time (104.3 vs. 119 min, p = ns) and complications did not decrease over time.CONCLUSION: A learning curve using the MitraClip(®) device does not appear to significantly affect acute MR reduction, hospital and 30-day mortality. Most likely, the proctor system leads to already high initial procedure success and relatively short procedure time.

U2 - 10.1007/s00392-014-0734-y

DO - 10.1007/s00392-014-0734-y

M3 - Journal article

C2 - 24924580

SN - 1861-0684

VL - 103

SP - 930

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JO - Clinical research in cardiology : official journal of the German Cardiac Society

JF - Clinical research in cardiology : official journal of the German Cardiac Society

IS - 11

ER -

Impact of the learning curve on outcome after transcatheter mitral valve repair: results from the German Mitral Valve Registry

Abstract

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