Impact of peptide:HLA complex stability for the identification of SARS-CoV-2-specific CD8+T cells

Keyphrases

• CD8+ T Cells 100%
• Peptide-HLA 100%
• Complex Stability 100%
• HLA System 100%
• Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) 100%
• Immunogenic Epitopes 33%
• False Discovery Rate 16%
• Deconvolution 16%
• Stability Analysis 16%
• T Cells 16%
• Epitope 16%
• Protective Immune Response 16%
• Convalescent 16%
• Peptide Pools 16%
• Tetramer Staining 16%
• Class I Alleles 16%
• COVID-19 16%
• SARS-CoV-2 Spike Protein 16%
• Selection Parameters 16%
• Peptide Selection 16%
• Patrolling 16%
• Dominant Epitope 16%

Biochemistry, Genetics and Molecular Biology

• T Cell 100%
• CD8 100%
• SARS Coronavirus 100%
• Peptide 100%
• Allele 22%
• Staining 11%
• Immune Response 11%
• Spike Protein 11%

Immunology and Microbiology

• Cytotoxic T-Cell 100%
• Severe Acute Respiratory Syndrome Coronavirus 2 100%
• Peptides 100%
• Epitope 55%
• Allele 22%
• Immune Response 11%
• T Cell 11%
• Staining 11%
• COVID-19 11%
• Spike Protein 11%