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Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery: Subanalysis from Scoli Risk 1 Prospective Study

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Harvard

Saigal, R, Lau, D, Berven, SH, Carreon, L, Dekutoski, MB, Kebaish, KM, Qiu, Y, Matsuyama, Y, Kelly, M, Dahl, BT, Mehdian, H, Pellisé, F, Lewis, SJ, Cheung, KM, Shaffrey, CI, Fehlings, MG, Lenke, LG, Ames, CP & AOSpine Knowledge Forum Deformity 2021, 'Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery: Subanalysis from Scoli Risk 1 Prospective Study', Spine, bind 46, nr. 7, s. E450-E457. https://doi.org/10.1097/BRS.0000000000003852

APA

Saigal, R., Lau, D., Berven, S. H., Carreon, L., Dekutoski, M. B., Kebaish, K. M., Qiu, Y., Matsuyama, Y., Kelly, M., Dahl, B. T., Mehdian, H., Pellisé, F., Lewis, S. J., Cheung, K. M., Shaffrey, C. I., Fehlings, M. G., Lenke, L. G., Ames, C. P., & AOSpine Knowledge Forum Deformity (2021). Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery: Subanalysis from Scoli Risk 1 Prospective Study. Spine, 46(7), E450-E457. https://doi.org/10.1097/BRS.0000000000003852

CBE

Saigal R, Lau D, Berven SH, Carreon L, Dekutoski MB, Kebaish KM, Qiu Y, Matsuyama Y, Kelly M, Dahl BT, Mehdian H, Pellisé F, Lewis SJ, Cheung KM, Shaffrey CI, Fehlings MG, Lenke LG, Ames CP, AOSpine Knowledge Forum Deformity. 2021. Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery: Subanalysis from Scoli Risk 1 Prospective Study. Spine. 46(7):E450-E457. https://doi.org/10.1097/BRS.0000000000003852

MLA

Vancouver

Author

Saigal, Rajiv ; Lau, Darryl ; Berven, Sigurd H ; Carreon, Leah ; Dekutoski, Mark B ; Kebaish, Khaled M ; Qiu, Yong ; Matsuyama, Yukihiro ; Kelly, Michael ; Dahl, Benny T ; Mehdian, Hossein ; Pellisé, Ferran ; Lewis, Stephen J ; Cheung, Kenneth Mc ; Shaffrey, Christopher I ; Fehlings, Michael G ; Lenke, Lawrence G ; Ames, Christopher P ; AOSpine Knowledge Forum Deformity. / Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery : Subanalysis from Scoli Risk 1 Prospective Study. I: Spine. 2021 ; Bind 46, Nr. 7. s. E450-E457.

Bibtex

@article{2a0b989777ba4844b55b1400c0abbda7,
title = "Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery: Subanalysis from Scoli Risk 1 Prospective Study",
abstract = "STUDY DESIGN: International, multi-center, prospective, longitudinal observational cohort.OBJECTIVE: To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery.SUMMARY OF BACKGROUND DATA: Adult spinal deformity surgery is associated with high morbidity, including risk of new post-operative motor deficit. It is unclear what effect new motor deficit has on HRQOL scores.METHODS: Adult spinal deformity patients were enrolled prospectively at 15 sites worldwide. Other inclusion criteria included major Cobb >80 degrees, C7-L2 curve apex, and any patient undergoing 3 column osteotomy. ASIA scores and standard HRQOL scores were recorded pre-op, 6 weeks, 6 months, and 2 years.RESULTS: 272 complex adult spinal deformity (ASD) patients enrolled. HRQOL scores were worse for patients with lower LEMS scores. Mean HRQOL changes at 6 weeks and 2 years compared to pre-op for patients with motor worsening were: ODI (+12.4 at 6 weeks and -4.7 at 2 years), SF-36v2 physical (-4.5 at 6 weeks and +2.3 at 2 years), SRS-22r (0.0 at 6 weeks and +0.4 at 2 years). Mean HRQOL changes for motor-neutral patients were: ODI (+0.6 at 6 weeks and -12.1 at 2 years), SF-36v2 physical (-1.6 at 6 weeks and +5.9 at 2 years), and SRS-22r (+0.4 at 6 weeks and +0.7 at 2 years). For patients with LEMS improvement, mean HRQOL changes were: ODI (-0.6 at 6 weeks and -16.3 at 2 years), SF-36v2 physical (+1.0 at 6 weeks and +7.0 at 2 years), and SRS-22r (+0.5 at 6 weeks and +0.9 at 2 years).CONCLUSION: In the subgroup of deformity patients who developed a new motor deficit, total HRQOLs and HRQOL changes were negatively impacted. Patients with more than 2 points of LEMS worsening had the worst changes, but still showed overall HRQOL improvement at 6 months and 2 years compared to pre-op baseline.LEVEL OF EVIDENCE: 3.",
author = "Rajiv Saigal and Darryl Lau and Berven, {Sigurd H} and Leah Carreon and Dekutoski, {Mark B} and Kebaish, {Khaled M} and Yong Qiu and Yukihiro Matsuyama and Michael Kelly and Dahl, {Benny T} and Hossein Mehdian and Ferran Pellis{\'e} and Lewis, {Stephen J} and Cheung, {Kenneth Mc} and Shaffrey, {Christopher I} and Fehlings, {Michael G} and Lenke, {Lawrence G} and Ames, {Christopher P} and {AOSpine Knowledge Forum Deformity}",
note = "Copyright {\textcopyright} 2020 Wolters Kluwer Health, Inc. All rights reserved.",
year = "2021",
month = apr,
day = "1",
doi = "10.1097/BRS.0000000000003852",
language = "English",
volume = "46",
pages = "E450--E457",
journal = "Spine (Philadelphia, 1976)",
issn = "0362-2436",
publisher = "Lippincott Williams & Wilkins",
number = "7",

}

RIS

TY - JOUR

T1 - Impact of New Motor Deficit on HRQOL after Adult Spinal Deformity Surgery

T2 - Subanalysis from Scoli Risk 1 Prospective Study

AU - Saigal, Rajiv

AU - Lau, Darryl

AU - Berven, Sigurd H

AU - Carreon, Leah

AU - Dekutoski, Mark B

AU - Kebaish, Khaled M

AU - Qiu, Yong

AU - Matsuyama, Yukihiro

AU - Kelly, Michael

AU - Dahl, Benny T

AU - Mehdian, Hossein

AU - Pellisé, Ferran

AU - Lewis, Stephen J

AU - Cheung, Kenneth Mc

AU - Shaffrey, Christopher I

AU - Fehlings, Michael G

AU - Lenke, Lawrence G

AU - Ames, Christopher P

AU - AOSpine Knowledge Forum Deformity

N1 - Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - STUDY DESIGN: International, multi-center, prospective, longitudinal observational cohort.OBJECTIVE: To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery.SUMMARY OF BACKGROUND DATA: Adult spinal deformity surgery is associated with high morbidity, including risk of new post-operative motor deficit. It is unclear what effect new motor deficit has on HRQOL scores.METHODS: Adult spinal deformity patients were enrolled prospectively at 15 sites worldwide. Other inclusion criteria included major Cobb >80 degrees, C7-L2 curve apex, and any patient undergoing 3 column osteotomy. ASIA scores and standard HRQOL scores were recorded pre-op, 6 weeks, 6 months, and 2 years.RESULTS: 272 complex adult spinal deformity (ASD) patients enrolled. HRQOL scores were worse for patients with lower LEMS scores. Mean HRQOL changes at 6 weeks and 2 years compared to pre-op for patients with motor worsening were: ODI (+12.4 at 6 weeks and -4.7 at 2 years), SF-36v2 physical (-4.5 at 6 weeks and +2.3 at 2 years), SRS-22r (0.0 at 6 weeks and +0.4 at 2 years). Mean HRQOL changes for motor-neutral patients were: ODI (+0.6 at 6 weeks and -12.1 at 2 years), SF-36v2 physical (-1.6 at 6 weeks and +5.9 at 2 years), and SRS-22r (+0.4 at 6 weeks and +0.7 at 2 years). For patients with LEMS improvement, mean HRQOL changes were: ODI (-0.6 at 6 weeks and -16.3 at 2 years), SF-36v2 physical (+1.0 at 6 weeks and +7.0 at 2 years), and SRS-22r (+0.5 at 6 weeks and +0.9 at 2 years).CONCLUSION: In the subgroup of deformity patients who developed a new motor deficit, total HRQOLs and HRQOL changes were negatively impacted. Patients with more than 2 points of LEMS worsening had the worst changes, but still showed overall HRQOL improvement at 6 months and 2 years compared to pre-op baseline.LEVEL OF EVIDENCE: 3.

AB - STUDY DESIGN: International, multi-center, prospective, longitudinal observational cohort.OBJECTIVE: To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery.SUMMARY OF BACKGROUND DATA: Adult spinal deformity surgery is associated with high morbidity, including risk of new post-operative motor deficit. It is unclear what effect new motor deficit has on HRQOL scores.METHODS: Adult spinal deformity patients were enrolled prospectively at 15 sites worldwide. Other inclusion criteria included major Cobb >80 degrees, C7-L2 curve apex, and any patient undergoing 3 column osteotomy. ASIA scores and standard HRQOL scores were recorded pre-op, 6 weeks, 6 months, and 2 years.RESULTS: 272 complex adult spinal deformity (ASD) patients enrolled. HRQOL scores were worse for patients with lower LEMS scores. Mean HRQOL changes at 6 weeks and 2 years compared to pre-op for patients with motor worsening were: ODI (+12.4 at 6 weeks and -4.7 at 2 years), SF-36v2 physical (-4.5 at 6 weeks and +2.3 at 2 years), SRS-22r (0.0 at 6 weeks and +0.4 at 2 years). Mean HRQOL changes for motor-neutral patients were: ODI (+0.6 at 6 weeks and -12.1 at 2 years), SF-36v2 physical (-1.6 at 6 weeks and +5.9 at 2 years), and SRS-22r (+0.4 at 6 weeks and +0.7 at 2 years). For patients with LEMS improvement, mean HRQOL changes were: ODI (-0.6 at 6 weeks and -16.3 at 2 years), SF-36v2 physical (+1.0 at 6 weeks and +7.0 at 2 years), and SRS-22r (+0.5 at 6 weeks and +0.9 at 2 years).CONCLUSION: In the subgroup of deformity patients who developed a new motor deficit, total HRQOLs and HRQOL changes were negatively impacted. Patients with more than 2 points of LEMS worsening had the worst changes, but still showed overall HRQOL improvement at 6 months and 2 years compared to pre-op baseline.LEVEL OF EVIDENCE: 3.

UR - http://www.scopus.com/inward/record.url?scp=85102909928&partnerID=8YFLogxK

U2 - 10.1097/BRS.0000000000003852

DO - 10.1097/BRS.0000000000003852

M3 - Journal article

C2 - 33290376

VL - 46

SP - E450-E457

JO - Spine (Philadelphia, 1976)

JF - Spine (Philadelphia, 1976)

SN - 0362-2436

IS - 7

ER -

ID: 62386365