Abstract
By electro-immunoprecipitation methods it was shown that antigen Tp-4 of Treponema pallidum, antigen TR-c of the Reiter treponeme and 'Common Antigen' of Pseudomonas aeruginosa are immunologically cross-reactive. This finding establishes a taxonomic relationship between T. pallidum and a wide range of bacteria. The cross-reactivity explains some false positive reactions in serodiagnostic treponemal tests for syphilis. The cross-reactivity may also play a role in a possible 'normal' immunity against infection with T. pallidum induced by antigens by the normal human bacterial flora.
Originalsprog | Engelsk |
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Tidsskrift | Acta pathologica et microbiologica Scandinavica |
Vol/bind | 92 |
Udgave nummer | 4 |
Sider (fra-til) | 183-8 |
Antal sider | 6 |
ISSN | 0108-0180 |
DOI | |
Status | Udgivet - aug. 1984 |
Udgivet eksternt | Ja |