Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy

Ruili Li; Jorgen Thorup; Cong Sun; Dina Cortes; Bridget Southwell; John Hutson

doi:10.1016/j.juro.2013.08.075

Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy

Ruili Li, Jorgen Thorup, Cong Sun, Dina Cortes, Bridget Southwell, John Hutson

Børne- og Ungeafdelingen

24 Citationer (Scopus)

Abstract

Undescended testis is the most common defect in male newborns. This condition is associated with increased risks of infertility and testicular malignancy due to abnormal germ cell development in the testes. Early surgery may limit such risks. We analyzed germ cell development vs age at orchiopexy using a germ cell marker and a Sertoli cell marker on testicular biopsies.

Originalsprog	Engelsk
Tidsskrift	The Journal of urology
Vol/bind	191
Udgave nummer	2
Sider (fra-til)	458-464
ISSN	0022-5347
DOI	https://doi.org/10.1016/j.juro.2013.08.075
Status	Udgivet - feb. 2014

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10.1016/j.juro.2013.08.075

Citationsformater

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title = "Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy",

abstract = "Undescended testis is the most common defect in male newborns. This condition is associated with increased risks of infertility and testicular malignancy due to abnormal germ cell development in the testes. Early surgery may limit such risks. We analyzed germ cell development vs age at orchiopexy using a germ cell marker and a Sertoli cell marker on testicular biopsies.",

author = "Ruili Li and Jorgen Thorup and Cong Sun and Dina Cortes and Bridget Southwell and John Hutson",

year = "2014",

month = feb,

doi = "10.1016/j.juro.2013.08.075",

language = "English",

volume = "191",

pages = "458--464",

journal = "The Journal of urology",

issn = "0022-5347",

publisher = "Wolters Kluwer Health",

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TY - JOUR

T1 - Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy

AU - Li, Ruili

AU - Thorup, Jorgen

AU - Sun, Cong

AU - Cortes, Dina

AU - Southwell, Bridget

AU - Hutson, John

PY - 2014/2

Y1 - 2014/2

N2 - Undescended testis is the most common defect in male newborns. This condition is associated with increased risks of infertility and testicular malignancy due to abnormal germ cell development in the testes. Early surgery may limit such risks. We analyzed germ cell development vs age at orchiopexy using a germ cell marker and a Sertoli cell marker on testicular biopsies.

AB - Undescended testis is the most common defect in male newborns. This condition is associated with increased risks of infertility and testicular malignancy due to abnormal germ cell development in the testes. Early surgery may limit such risks. We analyzed germ cell development vs age at orchiopexy using a germ cell marker and a Sertoli cell marker on testicular biopsies.

U2 - 10.1016/j.juro.2013.08.075

DO - 10.1016/j.juro.2013.08.075

M3 - Journal article

C2 - 24012581

SN - 0022-5347

VL - 191

SP - 458

EP - 464

JO - The Journal of urology

JF - The Journal of urology

IS - 2

ER -

Immunofluorescent Analysis of Testicular Biopsies with Germ Cell and Sertoli Cell Markers Shows Significant MVH Negative Germ Cell Depletion with Older Age at Orchiopexy

Abstract

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