Imaging prostate cancer: an update on positron emission tomography and magnetic resonance imaging

Kirsten Bouchelouche, Baris Turkbey, Peter Choyke, Jacek Capala

46 Citationer (Scopus)

Abstract

Prostate cancer is a common cancer in men and continues to be a major health problem. Imaging plays an essential role in the clinical management of patients. An important goal for prostate cancer imaging is more accurate disease characterization through the synthesis of anatomic, functional, and molecular imaging information. Developments in imaging technologies, specifically magnetic resonance imaging (MRI) and positron emission tomography (PET)/computed tomography (CT), have improved the detection rate of prostate cancer. MRI has improved lesion detection and local staging. Furthermore, MRI allows functional assessment with techniques such as diffusion-weighted MRI, MR spectroscopy, and dynamic contrast-enhanced MRI. The most common PET radiotracer, (18)F-fluorodeoxyglucose, is not very useful in prostate cancer. However, in recent years other PET tracers have improved the accuracy of PET/CT imaging of prostate cancer. Among these, choline (labeled with (18)F or (11)C), (11)C-acetate, and (18)F-fluoride have demonstrated promising results, and other new radiopharmaceuticals are currently under evaluation in preclinical and clinical studies.
OriginalsprogEngelsk
TidsskriftCurrent Urology Reports
Vol/bind11
Udgave nummer3
Sider (fra-til)180-90
Antal sider11
ISSN1527-2737
DOI
StatusUdgivet - 1 maj 2010

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