IgE-mediated chlorhexidine allergy: a new occupational hazard?

Vasantha Nagendran; Jennifer Wicking; Anjali Ekbote; Theresa Onyekwe; Lene Heise Garvey

doi:10.1093/occmed/kqp042

IgE-mediated chlorhexidine allergy: a new occupational hazard?

Vasantha Nagendran, Jennifer Wicking, Anjali Ekbote, Theresa Onyekwe, Lene Heise Garvey

Allergi, Hud- og Kønssygdomme

59 Citationer (Scopus)

Abstrakt

Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

Originalsprog	Engelsk
Tidsskrift	Occupational Medicine
Vol/bind	59
Udgave nummer	4
Sider (fra-til)	270-2
Antal sider	3
ISSN	0962-7480
DOI	https://doi.org/10.1093/occmed/kqp042
Status	Udgivet - 2009

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10.1093/occmed/kqp042

Citationsformater

@article{4497b93d0ac44996a27433a5c7456442,

title = "IgE-mediated chlorhexidine allergy: a new occupational hazard?",

abstract = "Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.",

keywords = "Adult, Anti-Infective Agents, Local, Chlorhexidine, Dermatitis, Occupational, Female, Great Britain, Hand Disinfection, Health Personnel, Hospitals, District, Humans, Hypersensitivity, Immediate, Immunoglobulin E, Infection Control, Male, Middle Aged, Questionnaires, Skin Tests",

author = "Vasantha Nagendran and Jennifer Wicking and Anjali Ekbote and Theresa Onyekwe and Garvey, {Lene Heise}",

year = "2009",

doi = "10.1093/occmed/kqp042",

language = "English",

volume = "59",

pages = "270--2",

journal = "Occupational Medicine",

issn = "0962-7480",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - IgE-mediated chlorhexidine allergy

T2 - a new occupational hazard?

AU - Nagendran, Vasantha

AU - Wicking, Jennifer

AU - Ekbote, Anjali

AU - Onyekwe, Theresa

AU - Garvey, Lene Heise

PY - 2009

Y1 - 2009

N2 - Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

AB - Chlorhexidine is an effective antimicrobial agent commonly used in UK hospitals, primarily for skin decontamination. Recent UK infection control guidelines recommend the use of 2% chlorhexidine solution in specific clinical settings, thus increasing chlorhexidine use by health care workers (HCWs). Chlorhexidine has been widely reported to cause IgE-mediated allergic reactions (from urticaria and angioedema to anaphylaxis) among patients undergoing surgery/invasive procedures. Despite its widespread use in health care settings, there are no reports of clinically confirmed occupational IgE-mediated chlorhexidine allergy.

KW - Adult

KW - Anti-Infective Agents, Local

KW - Chlorhexidine

KW - Dermatitis, Occupational

KW - Female

KW - Great Britain

KW - Hand Disinfection

KW - Health Personnel

KW - Hospitals, District

KW - Humans

KW - Hypersensitivity, Immediate

KW - Immunoglobulin E

KW - Infection Control

KW - Male

KW - Middle Aged

KW - Questionnaires

KW - Skin Tests

U2 - 10.1093/occmed/kqp042

DO - 10.1093/occmed/kqp042

M3 - Journal article

C2 - 19325161

VL - 59

SP - 270

EP - 272

JO - Occupational Medicine

JF - Occupational Medicine

SN - 0962-7480

IS - 4

ER -

IgE-mediated chlorhexidine allergy: a new occupational hazard?

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